Results 21 to 30 of about 20,387,570 (303)

A metabolomic analysis of thiol response for standard and modified N‐acetyl cysteine treatment regimens in patients with acetaminophen overdose

Clinical and Translational Science, 2021
N‐acetylcysteine (NAC) is an antidote to prevent acetaminophen (paracetamol‐APAP)‐induced acute liver injury (ALI). The 3‐bag licensed 20.25 h standard regimen, and a 12 h modified regimen, are used to treat APAP overdose.
James W Dear, Mei Li Ng, D. Nicholas Bateman, Pakkiri Leroy Sivappiragasam, Hyungwon Choi, Benjamin Bing Jie Khoo, Baharudin Ibrahim, Chester Lee Drum   +7 more
doaj   +1 more source

Coupled Oscillators - Complex but Not Complicated Cardiovascular and Brain Interactions. [PDF]

, 2007
In coupled nonlinear oscillators approach, the framework that has been used for the studies of cardiovascular and brain oscillations. As background, it describes the human CVS and present results of time-frequency analysis using wavelet transforms of ...
Stefanovska, Aneta
core   +4 more sources

Emergency Valve-in-Valve Transcatheter Aortic Valve Implantation for the Treatment of Acute Stentless Bioprosthetic Aortic Insufficiency and Cardiogenic Shock

Case Reports in Cardiology, 2018
Bioprosthetic aortic valve degeneration may present as acute, severe aortic regurgitation and cardiogenic shock. Such patients may be unsuitable for emergency valve replacement surgery due to excessive risk of operative mortality but could be treatable ...
Ivan D. Hanson, Pratik K. Dalal, Brian M. Renard, George S. Hanzel, Alessandro Vivacqua   +4 more
doaj   +1 more source

Self-Expandable Transcatheter Aortic Valve Frame Infolding: An Increasingly Recognized Complication

European Journal of Case Reports in Internal Medicine, 2020
Transcatheter aortic valve replacement (TAVR) with either a balloon-expandable or a self-expandable transcatheter heart valve (THV) is an approved therapy for patients with symptomatic severe aortic stenosis and high or intermediate surgical risk.
Gurpreet Singh, Vien Le, Robert Wiechmann, Steven Schreiter   +3 more
doaj   +1 more source

PPARs and the Cardiovascular System

Antioxidants & Redox Signaling, 2009
Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear hormone-receptor superfamily. Originally cloned in 1990, PPARs were found to be mediators of pharmacologic agents that induce hepatocyte peroxisome proliferation. PPARs also are expressed in cells of the cardiovascular system.
Hamblin, Milton, Chang, Lin, Fan, Yanbo, Zhang, Jifeng, Chen, Y. Eugene   +4 more
openaire   +4 more sources

Master of the Masquerade: An Atypical Presentation of Acute Aortic Dissection

Case Reports in Cardiology, 2020
Acute aortic dissection (AAD) is associated with unacceptably high mortality rate. As such, early diagnosis and aggressive management are essential in order to avoid life-threatening complications.
Ramy Mando, Daniel Tim, Anthony DeCicco, Justin Trivax, Ivan Hanson   +4 more
doaj   +1 more source

Hemodynamic Support Using Percutaneous Transfemoral Impella 5.0 and Impella RP for Refractory Cardiogenic Shock

Case Reports in Cardiology, 2019
Acute myocardial infarction (AMI) resulting in cardiogenic shock continues to be a substantial source of morbidity and mortality despite advances in recognition and treatment.
Pratik K. Dalal, Amy Mertens, Dinesh Shah, Ivan Hanson   +3 more
doaj   +1 more source

Immunosuppressive Agents—Effects on the Cardiovascular System and Selected Metabolic Aspects: A Review

, 2023
The widespread use of immunosuppressive drugs makes it possible to reduce inflammation in autoimmune diseases, as well as prevent transplant rejection in organ recipients. Despite their key action in blocking the body’s immune response, these drugs
Marta Grabowska, Bianka Opałka, Michał Żołnierczuk   +2 more
core   +1 more source

Efficacy and Safety of Electrosurgical Balloon-Assisted Leaflet Modification to Prevent Coronary Obstruction During Transcatheter Aortic Valve Replacement

Structural Heart
Background: Coronary obstruction (CO) during transcatheter aortic valve replacement (TAVR) is associated with significant morbidity and mortality. UNICORN (Undermining Iatrogenic Coronary Obstruction with Radiofrequency Needle) is a novel technique ...
Mostafa Naguib, MD, Chantal Y. Asselin, MSc, MD, Robert Kipperman, MD, Leo Marcoff, MD, Kostantinos P. Koulogiannis, MD, Linda Gillam, MD, MPH, Benjamin van Boxtel, MD, John Brown, III, MD, Philippe Généreux, MD, Gennaro Giustino, MD   +9 more
doaj   +1 more source

Countering impaired glucose homeostasis during catch-up growth with essential polyunsaturated fatty acids: is there a major role for improved insulin sensitivity?

Nutrition & Diabetes, 2021
Background/Objectives Catch-up growth, an important risk factor for later obesity and type 2 diabetes, is often characterized by a high rate of fat deposition associated with hyperinsulinemia and glucose intolerance.
Julie Calonne, Helena Marcelino, Christelle Veyrat-Durebex, Isabelle Scerri, Abdul G. Dulloo   +4 more
doaj   +1 more source