Results 21 to 30 of about 2,065,380 (330)

Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]

, 2018
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J., Petrie, John R., Touyz, Rhian M.   +2 more
core   +1 more source

Following hearts, one cell at a time: recent applications of single-cell RNA sequencing to the understanding of heart disease

Nature Communications, 2018
The mammalian heart contains heterogeneous cell types contributing to pathological changes in cardiac disease. In this Comment, we explore how single-cell transcriptomic approaches are unveiling intricate cellular mechanisms and gene co-expression ...
Matthew Ackers-Johnson, Wilson Lek Wen Tan, Roger Sik-Yin Foo   +2 more
doaj   +1 more source

A metabolomic analysis of thiol response for standard and modified N‐acetyl cysteine treatment regimens in patients with acetaminophen overdose

Clinical and Translational Science, 2021
N‐acetylcysteine (NAC) is an antidote to prevent acetaminophen (paracetamol‐APAP)‐induced acute liver injury (ALI). The 3‐bag licensed 20.25 h standard regimen, and a 12 h modified regimen, are used to treat APAP overdose.
James W Dear, Mei Li Ng, D. Nicholas Bateman, Pakkiri Leroy Sivappiragasam, Hyungwon Choi, Benjamin Bing Jie Khoo, Baharudin Ibrahim, Chester Lee Drum   +7 more
doaj   +1 more source

Exercise and the Cardiovascular System [PDF]

Cardiology Research and Practice, 2012
There are alarming increases in the incidence of obesity, insulin resistance, type II diabetes, and cardiovascular disease. The risk of these diseases is significantly reduced by appropriate lifestyle modifications such as increased physical activity.
Saeid Golbidi, Ismail Laher
openaire   +3 more sources

Emergency Valve-in-Valve Transcatheter Aortic Valve Implantation for the Treatment of Acute Stentless Bioprosthetic Aortic Insufficiency and Cardiogenic Shock

Case Reports in Cardiology, 2018
Bioprosthetic aortic valve degeneration may present as acute, severe aortic regurgitation and cardiogenic shock. Such patients may be unsuitable for emergency valve replacement surgery due to excessive risk of operative mortality but could be treatable ...
Ivan D. Hanson, Pratik K. Dalal, Brian M. Renard, George S. Hanzel, Alessandro Vivacqua   +4 more
doaj   +1 more source

Cardiovascular System Modeling [PDF]

Computational and Mathematical Methods in Medicine, 2012
Mathematical models and numerical simulations of the cardiovascular system are very useful for understanding the mechanisms influencing its function and its physiological and pathological processes. This modeling research increases the potential for developing new diagnostic and therapeutic cardiovascular techniques or devices and is also helpful for ...
Xia, Ling, Murray, Alan, Zheng, Dingchang, Liu, Feng, Ye, Xuesong, Ning, Gangmin   +5 more
openaire   +3 more sources

Master of the Masquerade: An Atypical Presentation of Acute Aortic Dissection

Case Reports in Cardiology, 2020
Acute aortic dissection (AAD) is associated with unacceptably high mortality rate. As such, early diagnosis and aggressive management are essential in order to avoid life-threatening complications.
Ramy Mando, Daniel Tim, Anthony DeCicco, Justin Trivax, Ivan Hanson   +4 more
doaj   +1 more source

Self-Expandable Transcatheter Aortic Valve Frame Infolding: An Increasingly Recognized Complication

European Journal of Case Reports in Internal Medicine, 2020
Transcatheter aortic valve replacement (TAVR) with either a balloon-expandable or a self-expandable transcatheter heart valve (THV) is an approved therapy for patients with symptomatic severe aortic stenosis and high or intermediate surgical risk.
Gurpreet Singh, Vien Le, Robert Wiechmann, Steven Schreiter   +3 more
doaj   +1 more source

Coil Embolization of Coronary-Cameral Fistula Complicating Revascularization of Chronic Total Occlusion

Case Reports in Cardiology, 2018
Traumatic vessel perforation is a potential complication of chronic total occlusion (CTO) percutaneous coronary artery intervention (PCI). A rare consequence of this complication is a coronary-cameral fistula. The management of this condition is not well
Amy Mertens, Pratik Dalal, Michael Ashbrook, Ivan Hanson   +3 more
doaj   +1 more source

Countering impaired glucose homeostasis during catch-up growth with essential polyunsaturated fatty acids: is there a major role for improved insulin sensitivity?

Nutrition & Diabetes, 2021
Background/Objectives Catch-up growth, an important risk factor for later obesity and type 2 diabetes, is often characterized by a high rate of fat deposition associated with hyperinsulinemia and glucose intolerance.
Julie Calonne, Helena Marcelino, Christelle Veyrat-Durebex, Isabelle Scerri, Abdul G. Dulloo   +4 more
doaj   +1 more source