Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Homoparental families and care
Prospectiva, 2015 This article outlines a reflection about care in homoparental families as a way to respond to the heteronormative pressures in the Western world, which usually disqualifies and rejects diverse families.
Ángela Marcela Andrade-Villegas +1 more
doaj
The shadow side of occupational therapy: Necropower, state racism and colonialism
Scandinavian Journal of Occupational TherapyBackground In the Global North, advances in occupational therapy benefitted unduly from the oppression, disablement and suffering of thousands of people in the South (and beyond).
Pier-Luc Turcotte, Dave Holmes
doaj +1 more source
Emerging Medicaid Accountable Care Organizations: The Role of Managed Care [PDF]
, 2012 Examines the Medicaid payment and care delivery systems in states working to develop accountable care organizations within Medicaid, how ACOs may be structured to fit into them, and how Medicaid ACOs differ from those in Medicare and the private ...
Sarah M. Kuszczak
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Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Adolescent Sexual and Reproductive Health:Report on an Assessment and Review of Training Materials [PDF]
Young people in Tanzania face a range of serious reproductive health risks – from early unwanted pregnancy and unsafe abortion to sexually transmitted infections, including HIV/AIDS.
Family Care International , (FCI) +1 more
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Care Management of Patients With Complex Health Care Needs [PDF]
, 2009 Explores how patients' complexity of healthcare needs, vulnerability, and age affect the cost and quality of their health care. Examines the potential for care management to improve quality of care and reduce costs, elements of success, and ...
Rachel Berry-Millett, Thomas Bodenheimer
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The significance of a ‘correct and uniform system of accounts’ to the administration of the Poor Law Amendment Act, 1834 [PDF]
, 2011 Care, Verna
core +1 more source
Immigrants in Health Care: Keeping Americans Healthy Through Care and Innovation [PDF]
, 2016 Immigrants play an outsized and imperative role in the U.S. health care industry. Combining existing data and profiles of immigrants across the health care spectrum, Immigrants in Health Care: Keeping Americans Healthy Through Care and Innovation ...
Marcia D. Hohn
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