Results 111 to 120 of about 14,283,857 (309)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Labour & Law IssuesThe Directive on improving working conditions in platform work challenges deeply entrenched inequalities in platform work by regulating some aspects of the labour process that remain unregulated in most EU Member States.
Nelli Kambouri
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
EludamosMeant as both a provocation and a prompt, ‘who cares about esports?’ opens the topic up to critical scrutiny at a time when the esports industry is in the midst of a(nother) serious contraction, even as there is a sizeable jump in the breadth and amount ...
Nicholas T. Taylor
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Exploring registered health professionals' assessment of older adults in care facilities : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy at Massey University, Turitea Campus, Palmerston North, New Zealand / [PDF]
, 2005 Older adults in care facilities are increasingly frail, with a number of co-existing conditions and complex health care needs. Before entry into a care facility, and while they are residing in a care facility, older adults are assessed by health ...
Roeters, Sylvia
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Caring for Form: Ali Smith and Contemporary Refugee Life-Writing
Czytanie LiteraturyRefugee life writing draws attention to the actual stories behind the statistics (100 million refugees worldwide, more than 3,000 people drowned while attempting to cross the Mediterranean in 2023 alone) and calls for solidarity across national and ...
Miriam Nandi
doaj +1 more source