Results 131 to 140 of about 5,900,632 (304)
Complementary Medicine Journal of Faculty of Nursing and Midwifery, 2020 Objective: Spiritual health of caregivers has association with the patients’ health, but less attention has been paid to spiritual self-care education in health programs.
Maryam Dalir +2 more
doaj
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
, 2018 Purpose: The study is an attempt at describing the psychological characteristics of caregivers of relatives with schizophrenia which contribute to deepening or reducing the negative consequences of care.
Jan Chodkiewicz, Joanna Siewierska
core +1 more source
Huli yanjiu, 2016 Objective:To investigate and analyze the influence of disability degree of elderly on care burden and quality of life of family caregivers.Methods:A total of 135 disabled elderly and their family caregivers received the assessment by using the Barthel ...
汤娟娟, 王俊杰, 汪永坚
doaj
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Impact of antiepileptic-drug treatment burden on health-care-resource utilization and costs [PDF]
, 2018 Krithika Rajagopalan,1 Sean D Candrilli,2 Mayank Ajmera2 1Sunovion Pharmaceuticals Inc, Marlborough, MA 01752, USA; 2RTI Health Solutions, Research Triangle Park, NC 27709, USA Background: Complex titration requirements and dosing of antiepileptic drugs (
Candrilli SD, Ajmera M, Rajagopalan K
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Investigating the Relationship between Resilience and the Care Burden in Caregivers of People with Spinal Cord Injuries Referred to the Iranian Spinal Cord Injury Support Association in 2021 [PDF]
مجله دانشگاه علوم پزشکی خراسان شمالیIntroduction: Caring burden is a situation that the caregiver faces during the care of a person with a spinal cord injury. Considering the significant level of stress and care burden created for caregivers in providing care, the concept of resilience ...
Yasaman Shahmoradi +2 more
doaj
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source