Results 111 to 120 of about 5,900,632 (304)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Burden of disease scenarios by state in the USA, 2022-50: a forecasting analysis for the Global Burden of Disease Study 2021. [PDF]
BACKGROUND: The capacity to anticipate future health issues is important for both policy makers and practitioners in the USA, as such insights can facilitate effective planning, investment, and implementation strategies. Forecasting trends in disease and
GBD 2021 US Burden of Disease and Forecasting Collaborators, +1 more
core +1 more source
Beyond Hours: Hidden Profiles of Underemployment in Australia
Social SciencesUnderemployment in Australia represents a critical facet of precarious work, shaped not only by insufficient hours and skill underutilisation but also by care responsibilities and financial insecurity.
Sora Lee, Woojin Kang
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Romancing the Carer - Intimate Relationships and Family Caring
, 2017 The topic of sexuality and romantic intimacy is not an easy one for many to discuss; in particular is it is often seen as secondary to the difficulties being faced in other aspects of life and in the relationship.
Care Alliance Ireland
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Ignorance is Bliss? Age, Misinformation, and Support for Women’s Representation
Replication data and code for the article "Ignorance is Bliss? Age, Misinformation, and Support for Women’s Representation" by Barry Burden and Yoshikuni Ono published in Public Opinion ...
Burden, Barry
core +1 more source
Administrative burden in primary care
Canadian Family PhysicianAdministrative burden contributes to the current primary care crisis. This critical review of the literature explores how primary care administrative burden is discussed, including how it is defined and what drivers and solutions have been identified.A systematic search of MEDLINE and CINAHL electronic databases for peer-reviewed original research ...
Oliver, Storseth +6 more
openaire +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
How Different Forms of Health Matter to Political Participation
Replication materials for "How Different Forms of Health Matter to Political Participation" by Burden, Fletcher, Herd, Jones, and Moynihan (Journal of ...
Burden, Barry
core +1 more source