Results 81 to 90 of about 5,997,028 (302)

Current practices and challenges in assisted reproductive technology care pathways in France and Belgium: the AMPLITUDE survey

Frontiers in Reproductive Health
IntroductionThis study aimed to evaluate current practices in assisted reproductive technology (ART) patient care, identifying potential areas for improvement.
Christine Wyns, Christophe Blockeel, Anne Guivarc’h-Lévêque, Géraldine Porcu-Buisson, Nelly Swierkowski-Blanchard, Nelly Swierkowski-Blanchard, Chadi Yazbeck, Chadi Yazbeck, Catherine Rongières   +8 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Conceptual framework on barriers and facilitators to implementing perinatal mental health care and treatment for women: the MATRIx evidence synthesis

Health and Social Care Delivery Research
Background Perinatal mental health difficulties can occur during pregnancy or after birth and mental illness is a leading cause of maternal death. It is therefore important to identify the barriers and facilitators to implementing and accessing perinatal
Rebecca Webb, Elizabeth Ford, Judy Shakespeare, Abigail Easter, Fiona Alderdice, Jennifer Holly, Rose Coates, Sally Hogg, Helen Cheyne, Sarah McMullen, Simon Gilbody, Debra Salmon, Susan Ayers   +12 more
doaj   +1 more source

Finland's digital care pathways revolution – Why call it a revolution?

Finnish Journal of eHealth and eWelfare
Evidence indicates that digital care pathways (DCPs) are more effective at improving patient outcomes than traditional methods. Personalized approaches and comprehensive content play key roles in supporting long‑term success and adherence.
Jaana Kotila, Minna Rauhala
doaj   +1 more source

Intensive care nurses' conceptions of a critical pathway in caring for aortic-surgery patients : a phenomenographic study

, 2013
The aim of the present study was to identify and describe intensive care nurses' different conceptions of a critical pathway in caring for patients that have undergone aortic-surgery. Individual semi-structured interviews with eight specialist registered
Rydlo, Cecilia, Lyckner, Sara, Bjurling-Sjöberg, Petronella,, Lyckner, Sara,, Rydlo, Cecilia,, Lyckner, S.,, Bjurling-Sjöberg, P.,, Bjurling-Sjöberg, Petronella, Engström, Gabriella, Engström, Gabriella,   +9 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

The Nottinghamshire Neurodiversity Network: building a multidisciplinary team of experts to improve pathways to care

Frontiers in Health Services
BackgroundNeurodevelopmental conditions (NDCs), including attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and tic disorders, are highly prevalent across the lifespan and are associated with substantial unmet need within ...
Blandine French, Madeleine Groom
doaj   +1 more source

Romancing the Carer - Intimate Relationships and Family Caring

, 2017
The topic of sexuality and romantic intimacy is not an easy one for many to discuss; in particular is it is often seen as secondary to the difficulties being faced in other aspects of life and in the relationship.
Care Alliance Ireland
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Exploring the care pathway for neurological conditions in a Gauteng rehabilitation hospital, South Africa

African Journal of Disability
Background: People with neurological conditions resulting in disabilities face a multitude of challenges in their journey of care. Existing evidence recommends exploring region-specific care pathways to understand the multi-faceted factors that influence
Prisha Alakram-Khelawon, Sonti Pilusa, Natalie Benjamin-Damons   +2 more
doaj   +1 more source