From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The relation between career anchors emotional intelligence and employability satisafaction among workers in the service industry [PDF]
The objective of this study was to determine the relationship between the career anchors (measured by the Career Orientations Inventory), emotional intelligence (measured by the Assessing Emotions Scale) and employability satisfaction (measured by a ...
Coetzee, Melinde, Schreuder, A.M.G.
core
Depressed Mood and Career Anchors in Russian Medical Students
Introduction. People in helping professions are more prone to emotional burnout and depression. Even at the university level, future physicians experience an increase in depressed mood.
Evgeniy B. Knyazev +6 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Prediction of objective and subjective career success by career anchors among lawyers and jurists
Background: Various research has been done about job success in different strata of society. But, there is little research that has examined the career success of lawyers and jurists.
fatemeh samiee
doaj
Professional advancement of women to leadership roles in Moroccan sports federations [PDF]
This study explores the dynamics of career anchors shaped by organizational, individual, and societal determinants in relation to women’s access to leadership positions in Moroccan sports federations.
Chaymaa Lotfy +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Orientation: The challenge of sustaining one’s employability in a highly dynamic and turbulent labour market places new demands on individuals’ ability to navigate their career development.
Rudolf M. Oosthuizen +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

