Results 81 to 90 of about 853,686 (274)

Research on the influence of psychological fatigue of short track speed skaters on sports motivation

Frontiers in Psychology
ObjectiveTo clarify the mediating effects of perceived social support and sense of career calling on the relationship between psychological fatigue and sports motivation in short track speed skaters.MethodsUsing a variety of research methods such as ...
Guoxing Zhang, Feng Tai, Shihao Wang
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

How Background Influences School Counselors' Career Calling: A Preliminary Study

Bulletin of Counseling and Psychotherapy
This study explores the variations in career calling among school counselors based on ethno-socio-demographic backgrounds, such as ethnicity, religion, employment status, age, and gender.
Robbani Alfan, M Solehuddin, Juntika Nurihsan, Yusi Riksa Yustiana   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Cross-cultural differences in career calling: a comparison between Italy and Argentina [PDF]

openQuesta tesi si propone di esplorare la chiamata professionale attraverso un approccio cross-culturale, prendendo in campione studenti italiani ed argentini. Nel primo capitolo si approfondisce il costrutto di chiamata professionale.
CAMPONOVO, VALENTINA ELISA
core  

Career Calling Across Culture And Generations

, 2022
This symposium brings together an international group of scholars discussing original contributions and insights on the experience of Career Calling across cultural and generational boundaries.
Dalla Rosa A., Duffy R. D., Vianello M.
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Calling and WEIRDness across cultures [PDF]

openThis study examines the complex construct of career calling and its effects on peoples lives. Its relationship with WEIRDness is important to understand the cross-cultural differences of the constructThis study examines the complex construct of ...
PAGNI, LIAM
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source