Results 91 to 100 of about 1,258,808 (299)

Company Start-Up Costs and Employment [PDF]

open access: yes
I study the role of company start-up costs for employment performance. The model is search equilibrium with a new concept for firms. Agents have an innate managerial ability and make a career choice to become either managers or workers.
Christopher A. Pissarides
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Psychiatry as a Career Choice Amna Awais1, Neha Nadeem1, Muhammad Kashif Mehmood 1, Ayesha

open access: yesJournal of Rawalpindi Medical College, 2019
Background: To determine frequency of students in Rawalpindi Medical University who would opt for psychiatry as their future career. Along with that we will determine the reasons which encourage or discourage students from choosing Psychiatry.
Amna Awais   +3 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

PROGRAM BIMBINGAN KARIR UNTUK MENINGKATKAN KEMAMPUAN PILIHAN KARIR PESERTA DIDIK:(Studi Deskiptif terhadap Peserta Didik Kelas IX SMP Negeri 2 Lembang Tahun Ajaran 2015/2016) [PDF]

open access: yes, 2016
Kehidupan remaja di dalam pendidikan merupakan awal kehidupan karirnya. Kemampuan dalam memilih karir sangat penting karena pengembangan karir akan berlangsung sepanjang hayat kehidupan.
Tresnasih, Ayunda
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Career Progression and Comparative Advantage [PDF]

open access: yes
This paper constructs and structurally estimates a dynamic occupational choice model that has two distinct features. First, an occupation is vertically and horizontally differentiated by a multidimensional task complexity measure.
Shintaro Yamaguchi
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Hubungan Rencana Karir dengan Motivasi Menyelesaikan Studi pada Mahasiswa S1 Bimbingan Konseling

open access: yesIndonesian Journal of Guidance and Counseling: Theory and Application, 2017
Final year students at the stage of development of early adulthood. One task at this stage is already to plan a career choice. But as student, completed the study is a phase that must be passed, wich was made reasearch that addresses the correlation ...
Ardian Yuniarto
doaj  

Career Choice, Marriage-Timing, and the Attraction of Unequals [PDF]

open access: yes
Both men and women wish to have a family and a rewarding career. In this paper, we show that the under-representation of women in high-powered professions may reflect a coordination failure in young women's marriage-timing decisions. Since investing in a
Habiba Djebbari, Sylvain Dessy
core  

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