Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Career counseling as an environmental support: Exploring influences on career choice, career decision-making self-efficacy, and career barriers [PDF]
This study was motivated by concerns regarding the difficult academic and career choices facing today’s college students as they navigate higher education and encounter career barriers along their paths.
Makela, Julia P.
core
Konformitas Teman Sebaya dan Ketepatan Pemilihan Karier pada Peserta Didik
Career choice is an important decision faced by every individual. Peer conformity is often one of the factors that can influence individual decisions, including career choice.
Eka Aryani +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A career of choice: attracting talented young people into house building [PDF]
The purpose of this research was to establish a better understanding of how young people view house building as a career choice and to provide insights to improve recruitment of those with enthusiasm and talent into the sector.
Bysshe, Simon +2 more
core
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
An exploratory study of the internal career orientation and the external career pattern of information technology workers in Nigeria [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This study sets out to explore the internal career orientations and the external career patterns of information technology (IT) workers in Nigeria.
Ituma, Afam Nnanna
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Psychiatry as a Career Choice Amna Awais1, Neha Nadeem1, Muhammad Kashif Mehmood 1, Ayesha
Background: To determine frequency of students in Rawalpindi Medical University who would opt for psychiatry as their future career. Along with that we will determine the reasons which encourage or discourage students from choosing Psychiatry.
Amna Awais +3 more
doaj
BAKALAURO PAKOPOS STUDENTŲ KETINIMO EITI PASIRINKTU PROFESINIU KELIU YPATUMAI: DVIEJŲ IMČIŲ ANALIZĖ
Straipsnyje nagrinėjami ketinimo eiti pasirinktu profesiniu keliu ypatumai. Pagrindiniai tyrimo uždaviniai – įvertinti, kaip ketinimą eiti pasirinktu profesiniu keliu prognozuoja pasitenkinimo pasirinkta profesija lygis, įsivaizduojamas realaus ir ...
Ieva Urbanavičiūtė
doaj +1 more source

