Results 101 to 110 of about 111,585 (300)

Career choice under uncertainty [PDF]

open access: yes, 2016
Contemporary theoretical literature on occupational choice consists mostly of models that treat choice outcomes as either deterministic or risky. This paper proposes taking a slightly more realistic perspective by constructing a general occupational ...
Konon, Alexander
core  

Chain-mediated effects of career self-efficacy and career planning between social support and career anxiety in college soccer players

open access: yesFrontiers in Psychology
The purpose of this study was to investigate the factors affecting the Career Anxiety of Chinese university high-level soccer players, to construct a chain mediation model, and to provide intervention suggestions to alleviate the Career Anxiety of this ...
Yu-Juan Feng   +4 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Factors affecting career-related decisions within the contemporary pharmacy workforce in Australia

open access: yesExploratory Research in Clinical and Social Pharmacy
Introduction: Pharmacists are essential to healthcare delivery in Australia, making effective workforce planning critical to ensure equitable health outcomes.
Jocelyn Bussing   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Early career training of quantity surveying professionals [PDF]

open access: yes, 2009
This research project addresses the issue of learning and development for new graduates in their early career. It is recognized that early career experience can play a significant part in lifelong professional capability and the support and knowledge ...
Hogg, Keith   +2 more
core  

Online career construction for a trauma survivor with career choice ambivalence

open access: yesSouth African Journal of Higher Education
This article reports on the online administration of career construction counselling for a trauma survivor who sought help in resolving her career-choice ambivalence (uncertainty). The participant was purposively selected from a group of people attending
J. G. Maree
doaj   +1 more source

A REFLECTION ON UNIVERSITY STUDIES AND FURTHER CAREER DEVELOPMENT OF CHOSEN CULS FACULTIES’ GRADUATES [PDF]

open access: yesJournal on Efficiency and Responsibility in Education and Science, 2010
The article is focused on professional orientation and direction of the careers of graduates of Faculty of Economics and Management (FEM) and Faculty of Agrobiology, Food and Natural Resources (FAFNR) at Czech University of Life Sciences Prague (CULS ...
Rymešová, Pavla, Kolman, Luděk
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

We Don’t Need No Education? Drivers and Deterrents in Career Decision-Making: A Comprehensive Model of Choosing Teaching

open access: yesEducation Sciences
This study presents and tests a model of vocational choice based on Gottfredson’s theory to explain the relatively low interest in teaching as a career and its underlying determinants.
Leehu Zysberg   +2 more
doaj   +1 more source

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