Results 81 to 90 of about 1,257,650 (344)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Career progression and formal versus on-the-job training [PDF]
, 2009 We model the choice of individuals to follow or not apprenticeship training and their subsequent career. We use German administrative data, which records education, labour market transitions and wages to estimate a dynamic discrete choice model of ...
Adda, J. +3 more
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Konformitas Teman Sebaya dan Ketepatan Pemilihan Karier pada Peserta Didik
Teraputik: Jurnal Bimbingan dan KonselingCareer choice is an important decision faced by every individual. Peer conformity is often one of the factors that can influence individual decisions, including career choice.
Eka Aryani +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Career choice under uncertainty
, 2016 Contemporary theoretical literature on occupational choice consists mostly of models that treat choice outcomes as either deterministic or risky. This paper proposes taking a slightly more realistic perspective by constructing a general occupational ...
Konon, Alexander
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PROGRAM BIMBINGAN KARIR UNTUK MENINGKATKAN KEMAMPUAN PILIHAN KARIR PESERTA DIDIK:(Studi Deskiptif terhadap Peserta Didik Kelas IX SMP Negeri 2 Lembang Tahun Ajaran 2015/2016) [PDF]
, 2016 Kehidupan remaja di dalam pendidikan merupakan awal kehidupan karirnya. Kemampuan dalam memilih karir sangat penting karena pengembangan karir akan berlangsung sepanjang hayat kehidupan.
Tresnasih, Ayunda
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BAKALAURO PAKOPOS STUDENTŲ KETINIMO EITI PASIRINKTU PROFESINIU KELIU YPATUMAI: DVIEJŲ IMČIŲ ANALIZĖ
Psichologija, 2009 Straipsnyje nagrinėjami ketinimo eiti pasirinktu profesiniu keliu ypatumai. Pagrindiniai tyrimo uždaviniai – įvertinti, kaip ketinimą eiti pasirinktu profesiniu keliu prognozuoja pasitenkinimo pasirinkta profesija lygis, įsivaizduojamas realaus ir ...
Ieva Urbanavičiūtė
doaj +1 more source
Academic Medicine, 1983 During the 1960s, early educational specialization and increasingly elective curricula were promoted as instructional advances. More recently, early educational specialization has been suggested as a solution to high educational costs and knowledge overload. In 1973 the McGill University Faculty of Medicine introduced a program of early specialization (
W D, Dauphinee, V L, Patel
openaire +3 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source