Results 61 to 70 of about 630,287 (300)

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Personality traits and career adaptability in adolescents: The mediating role of core self-evaluations [PDF]

Psihologija
The aim of this study was to extend previous findings on antecedents of career adaptability in adolescence. Drawing on career construction theory and the distal-proximal theory of motivation, we investigated the mediating role of core self-evaluations in
Šimunović Mara
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Construct Definition Methodology and Generalizability Theory Applied to Career Education Measurement

, 2022
AbstractThe field of career education measurement is in disarray. Evidence mounts that today’s career education instruments are verbal ability measures in disguise. A plethora of trait names such as career maturity, career development, career planning, career awareness, and career decision making have, in the last decade, appeared as labels to scales ...
A. Jackson Stenner, Richard J. Rohlf
openaire   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

The double-edged sword effect of perceived underemployment on the career satisfaction of new employment form workers

Frontiers in Organizational Psychology
IntroductionAs an important component of the modern economy, the career satisfaction of new employment form workers directly impacts individual work efficiency, corporate sustainability.
Chunxiang Fu, Haoran Wang
doaj   +1 more source

Mediated Bodies: The construction of a Wife, Mother, and the Female Body in Television Sitcoms: Roseanne [PDF]

, 2013
After first examining several theoretical concepts related to the construction of gender on television and the way in which women are characterized, this paper examines the television show Roseanne to explore the way it changed the representation of a ...
Ghanoui, Saniya Lee
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Adapt to Survive? Attenuating Indirect Effects of Career Adaptability on Exhaustion via Career Insecurity

Scandinavian Journal of Work and Organizational Psychology
The present study analyzed whether career adaptability is negatively related to exhaustion. Based on the conservation of resources theory, we argue that career insecurity is a connecting variable in the link between career adaptability and exhaustion. We
Daniel Spurk, Annabelle Hofer, Simone Kauffeld, Luisa Barthauer, Nora Nixon   +4 more
doaj   +1 more source