Results 51 to 60 of about 1,001,759 (302)
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Rehabilitation career counseling self-efficacy
Meaningful work promotes individual independence and is important to holistic well-being. In regard to counseling, career counseling services are of upmost importance to help clients obtain and sustain employment.
Courtney Evans +2 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Career Prospects of Substance-Dependent Individuals Following a Return to Work: A Qualitative Study [PDF]
Objective: The present study aimed to investigate the job prospects of recovering substance-dependent people after returning to work. Method: This was a qualitative study based on a phenomenological approach.
Marziye Dorali +2 more
doaj
The Working Alliance in Career Counseling : A Systematic Overview
The research related to the working alliance in career counseling is reviewed in this manuscript. This review indicates that the working alliance does typically increase over the course of career counseling.
Barón, Paola M. Hernandez +2 more
core +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The technological revolution, the ever-changing economic and political conditions, and the resulting changes in life and work environments impede career planning for young people and pose challenges for career counselors in career orientation.
Birutė Pociūtė +2 more
doaj +1 more source
Effectiveness of career counseling and the impact of the working alliance.
This study analyzes the role of the working alliance on the life satisfaction and career decision difficulties of clients participating in career counseling in Switzerland.
Rossier, J., Masdonati, J., Massoudi, K.
core +1 more source

