Results 71 to 80 of about 379,106 (305)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
مجله علوم روانشناختی, 2022 Background: In a world where the phenomenon of job loss is spreading rapidly, it is essential to be willing to invest continuously in a diverse career path that will lead to savings in human, social and psychological capital.
abed majidi +3 more
doaj
Family Therapy; An Approach To Strengthen Islamic Career Counseling
Konseling Religi: Jurnal Bimbingan Konseling Islam, 2019 Research on families, especially parents, both the role and parenting style in the household, are not counted. However, problems that arise and originate from the family sphere come alternately.
Alfin Miftahul Khairi
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
EFEKTIVITAS KONSELING KARIR NARATIF UNTUK MENGEMBANGKAN KEMATANGAN KARIR MAHASISWA [PDF]
, 2016 Penelitian dilatarbelakangi oleh temuan pada mahasiswa yang mengalami masalah karir. Penelitian bertujuan menguji keefektifan konseling karir naratif untuk mengembangkan kematangan karir mahasiswa.
Wati, Caroline Lisa Setia
core
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Pathways from caring and engaging adults to youth vocational identity: the mediational roles of career search self-efficacy and goal capacity [PDF]
, 2017 This study examines the role played by access to caring and engaging adults, career search self-efficacy (CSSE), and goal capacity in the development of youth vocational identity.
Chen, Zi, Solberg, V. Scott H.
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Occupation Profile: Psychologists, October 6, 2017 [PDF]
, 2017 Diagnose or evaluate mental and emotional disorders of individuals through observation, interview, and psychological tests, and formulate and administer programs of treatment. Belongs to the Health Science career cluster and Counseling and Therapeutic
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source