Results 101 to 110 of about 140,915 (300)

Career Counselling to Persons with Special Needs in the Context of Positive Psychology

open access: yesRevija za Elementarno Izobraževanje
Recently, the advantages or strengths of the individual have become important or even dominant in personal counselling. The basis for such a counselling approach can be found in positive psychology.
Janez Drobnic
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Towards the very nature of career, career guidance and counselling

open access: yesSA Journal of Industrial Psychology, 2005
The literature on career calls for a transformation and redefinition of career. In this paper we take a step back and ask: ‘what is a career?’. Careers as works are presented; those entities that set up and formed the world in which humans live and have ...
C W T Joubert, F Crous
doaj   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

More questions than answers: the role of practitioner research in professional practice. [PDF]

open access: yes, 2011
The concept of the career guidance practitioner viewing themselves as a professional is currently being challenged (Colley and Lewin, 2008; Greer, 2009).
Hutchinson, Jo, Neary, Siobhan
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Career Decision Ambivalence and Career Counseling Change Ambivalence in Career Counseling

open access: yesJournal of Career Development
The concept of ambivalence has received little attention within the field of vocational psychology. In this article, we distinguish between two types of ambivalence that may surface during the career counseling process: career decision ambivalence (i.e., ambivalence between career options) and career ...
Shékina Rochat   +2 more
openaire   +2 more sources

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