Results 81 to 90 of about 141,975 (298)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Horyzonty Wychowania, 2019 RESEARCH OBJECTIVE: The aim of the article is to present strengths and weaknesses of the Polish system of vocational guidance and career counselling for convicts on the example of occupational activation forms.
Daria Joanna Becker-Pestka
doaj
Professionalism in Careers [PDF]
, 2016 This briefing paper sets out the background, evidence and key issues relating to professionalism in careers work in England. The work is produced on behalf of Careers England and the Career Development Institute (CDI), but the paper does not represent ...
Hooley, Tristram +2 more
core +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
The Youth Guarantee and lifelong guidance [PDF]
, 2013 The European Youth Guarantee is an initiative to help link young people aged 16 - 14 to the labour market across all member states. The paper is a Concept Note commissioned by the policy network to explore how guidance activities are being implemented in
Borbély-Pecze, Tibor Bors +1 more
core +1 more source
Everything comes down to money? Migration and working life trajectories in a (post-)socialist context [PDF]
, 2011 Using 25 life histories of Poles, this paper addresses the way in which migration has had an impact upon the trajectories of individuals’ working lives both under socialism and after 1989.
Sliwa, M., Taylor, Becky
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Careers Education: An Effective Tool for Poverty Reduction [PDF]
, 2008 Education plays an important role in enhancing the quality of life of people, both old and young. However, the quality of education someone receives per time determines the impact and contributions he or she makes in terms of poverty reduction, income ...
Moses, Chinonye, Love
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
The (Un)Attractiveness of Vocational and Technical Education: Theoretical Background
Center for Educational Policy Studies Journal, 2014 This paper considers the problem of the lack of attractiveness of vocational and technical education via a review of legislation on counselling practices, implementing documents, and the social factors by means of which the education system can influence
Miha Lovšin
doaj +1 more source