Results 71 to 80 of about 141,272 (299)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Online career construction for a trauma survivor with career choice ambivalence

open access: yesSouth African Journal of Higher Education
This article reports on the online administration of career construction counselling for a trauma survivor who sought help in resolving her career-choice ambivalence (uncertainty). The participant was purposively selected from a group of people attending
J. G. Maree
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The Relationship Between Career Patterns And Personality Types

open access: yesSA Journal of Industrial Psychology, 2002
Contemporary career research emphasises the need for career counselling practices that will assist individuals in shifting from linear career preferences to non-linear career patterns.
M. Coetzee, A. M.G. Schreuder
doaj   +1 more source

Professionalism in Careers [PDF]

open access: yes, 2016
This briefing paper sets out the background, evidence and key issues relating to professionalism in careers work in England. The work is produced on behalf of Careers England and the Career Development Institute (CDI), but the paper does not represent ...
Hooley, Tristram   +2 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Kariérové cesty intelektovo nadaných ľudí

open access: yesPsychologie pro Praxi, 2019
In comparison with other areas of lives of intellectually gifted, their career development is relatively rarely discussed and researched. In this overview study specific problems that gifted students face when choosing their careers (such as ...
Eva Rajčániová
doaj   +1 more source

Life-design counselling for survivors of family violence in resource-constrained areas

open access: yesSouth African Journal of Education, 2020
The purpose of this study was to explore and assess the feasibility of counselling based on life-design principles in enhancing the career resilience of children who are exposed to family violence. The research project involved a QUALITATIVE–quantitative
Cobus J. Venter , Jacobus G. Maree
doaj   +1 more source

Promoting healthy transition from college to work market throughout seminars: the building of the therapeutic relationship [PDF]

open access: yes, 2009
This communication presents a specialized preventive career intervention – the Career Self-Management Seminar (CSMS; Taveira et al., 2006 – forms A and B).
Loureiro, Nazaré   +2 more
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

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