Results 61 to 70 of about 6,484,134 (246)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Career Development Framework [PDF]
, 2021 This document introduces the CDI’s Career Development Framework to careers professionals, educators and other professionals who work supporting people to develop their careers.
Hooley, Tristram
core
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
FAKTOR-FAKTOR YANG MENENTUKAN KEBIMBANGAN KARIER PADA SISWA SMA KELAS XII
Jurnal Psikologi Undip, 2019 Career decision is one of the major issue among XII grade of high school students, particularly choosing major in university. Most of high school students experience career indecision.
Sari Zakiah Akmal
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Personality and career decision making in undergraduates
RELIEVE: Revista Electrónica de Investigación y Evaluación Educativa, 2011 The relationships between personality and career decision making in undergraduates are analyzed in this work. The hypothesis is that efficient personality is associated with the more mature process of career decision making.
Cabrera, Lidia +1 more
doaj
Career Decision-Making Difficulties: Why Exploration Alone Is Not Enough for High School Students
Gadjah Mada Journal of Professional PsychologyCareer exploration is important for high school students to face career decision-making difficulties. This study aims to investigate the effect of career exploration training on career decision-making difficulties among 12th-grade high school students. A
Janice Grace Lusiani Larasati Simanjuntak
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Factors that influence career uncertainty in high school students [PDF]
, 2001 Plan BWhile not a new phenomenon, career uncertainty among high school students remains a constant challenge for high school counselors as they search for a career decision making process that is both developmentally comprehensive and designed to prepare
Schmidt, Lisa M.
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source