Results 71 to 80 of about 6,484,134 (246)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Psychoeducational Group Assisted with Profession Puppets to Improve Students’ Career Decision Making

Bulletin of Counseling and Psychotherapy, 2020
Career decision making is very important for individuals. In the adolescent phase, career decision making will play an important role in career development for the future of the individual itself.
Meitasari Meitasari, Hernisawati Hernisawati, Aprezo Pardodi Maba   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Career calling, ethical sensitivity, and decision-making ability in intensive care nurses: a mediating effect model

Frontiers in Psychology
AimsTo investigate the simultaneous effects of ethical sensitivity and career calling on intensive care nurses’ decision-making ability.MethodsA total 361 intensive care nurses in Hubei Province were selected as survey subjects.
Ke Wang, Yuanyuan Mi, Yanli Wu, Huimin Sun   +3 more
doaj   +1 more source

Navigating Career Decision-Making

, 2023
Career decision-making is a multifaceted and complex process that holds significant importance for college students facing delayed employment [1]. Understanding how to navigate this process becomes even more important for these people since they face ...
Minh-Phuong Thi Duong
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

KONSELING KARIR DENGAN MENGGUNAKAN CAREER INFORMATION-PROCESSING MODEL UNTUK MEMBANTU CAREER DECISION-MAKING

Psympathic: Jurnal Ilmiah Psikologi, 2017
Having graduated from senior high school, most of high school students continue their education to university level. This research aimed to find effectiveness of career counseling by using career information-processing model to assist career decision ...
Fatma Nur Aqmarina, Riana Sahrani, Rahmah Hastuti   +2 more
doaj   +1 more source

Waiting for a career epiphany - a barrier to decision-making? [PDF]

, 2018
The desire for a career epiphany, a sudden realisation of a future career, can often feature as an unspoken wish in career conversations with students and graduates.
Cunningham, E.A, Houston, K, Houston, Kathleen, Cunningham, EA   +3 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source