Results 81 to 90 of about 4,045,619 (295)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Enhancing professionalism - progressing the career development sector [PDF]
, 2015 Much has changed in the career development sector since the launch of the Careers Profession Task Force report, ‘Towards a Strong Careers Profession’ in 2010.
Neary, Siobhan +2 more
core
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
PENGEMBANGAN MODEL E-CAREER UNTUK MENINGKATKAN KEPUTUSAN KARIR SISWA SMA NEGERI 3 MAKASSAR
Jurnal Psikologi Pendidikan dan Konseling, 2016 This study aims: (1) To develop career information service model based on electronic media (e-career) which acceptable in improving students’ career decision at SMAN 3 Makassar.
Fadilla Fasha +2 more
doaj
Developmental issues in career maturity and career decision status
, 2001 Full ...
Patton, Wendy A., Creed, Peter A.
core
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
International Journal of Adolescence and YouthParental interference in career choices can expose adolescents to the risk of school burnout and depressive symptoms. The present study aimed to investigate the relationship between career-related parental interference, school burnout, depressive ...
Giacomo Angelini +2 more
doaj +1 more source
Humanitas: Indonesian Psychological Journal, 2019 Making a career decision is one of the most complex development tasks faced by high school students who will graduate from school. Students need to believe that they would succeed in their effort to do the necessary tasks during the process of career ...
Melly Preston, Rose Mini Agoes Salim
doaj +1 more source
A career in career - understanding what career looks like in the career development sector [PDF]
, 2017 There is little known about the careers workforce in the UK. This research focuses on developing a better understanding of who chooses to become a career development practitioner, their motivation, the transferable skills they bring with them and how ...
Neary, S. +2 more
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