Results 41 to 50 of about 87,305 (250)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Role of Father and Mother Attachment on The Career Decision-Making Style of Female Balinese High School Students

open access: yesJurnal Psikiatri Surabaya
Introductions: Career decision-making in female Balinese high school students is influenced by parental attachment, particularly in a patriarchal cultural context.
Laksmi Ananda Dewi   +1 more
doaj   +1 more source

Promoting Career Maturity through Cognitive Behavior Therapy in Group Counseling: A Pathway to Informed Decision-Making for Students

open access: yesJurnal Bimbingan dan Konseling Terapan, 2023
This article explores the potential of Cognitive Behavior Therapy (CBT) in group counseling to enhance career maturity and informed decision-making among students.
Nur Khofifah   +2 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

KONSELING KARIR DENGAN MENGGUNAKAN CAREER INFORMATION-PROCESSING MODEL UNTUK MEMBANTU CAREER DECISION-MAKING

open access: yesPsympathic: Jurnal Ilmiah Psikologi, 2017
Having graduated from senior high school, most of high school students continue their education to university level. This research aimed to find effectiveness of career counseling by using career information-processing model to assist career decision ...
Fatma Nur Aqmarina   +2 more
doaj   +1 more source

Does conformity occur during students' decision making for their careers?

open access: yesAsian Journal of Assessment in Teaching and Learning, 2020
Students between ages 13 to 18 years old are exposed to have career development assignments of life focused on the education field such as choosing majors or career fields.
Putri Fathia Fadilla   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

TO EMBRACE CAREER DECISION MAKING IN STEM EDUCATION [PDF]

open access: yesEDULEARN Proceedings, 2019
Higher and Vocational Education students in STEM (Science, Technology, Engineering, and Maths) must embrace the reality of career decision making from the early beginning of their curriculum. They have to develop a set of skills related to decision-making to ensure that their professional career is to be directed to intended goals, professionnal and ...
Chelin, Nathalie   +5 more
openaire   +2 more sources

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