Results 51 to 60 of about 87,305 (250)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Personality and career decision making in undergraduates

RELIEVE: Revista Electrónica de Investigación y Evaluación Educativa, 2011
The relationships between personality and career decision making in undergraduates are analyzed in this work. The hypothesis is that efficient personality is associated with the more mature process of career decision making.
Cabrera, Lidia, Bethencourt, José-Tomás   +1 more
doaj  

Career Decision-Making Difficulties: Why Exploration Alone Is Not Enough for High School Students

Gadjah Mada Journal of Professional Psychology
Career exploration is important for high school students to face career decision-making difficulties. This study aims to investigate the effect of career exploration training on career decision-making difficulties among 12th-grade high school students. A
Janice Grace Lusiani Larasati Simanjuntak
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Career Decision-Making among Pediatric Residents [PDF]

Medical Education Online, 2005
Knowledge of the timing and process of residents' career decisionmaking could improve mentoring, career counseling and subspecialty recruitment efforts. However, knowledge about the timing of career decisions made by pediatric residents is lacking.To examine the timing of career decision-making among pediatric residents.We conducted a cross-sectional ...
Laura, Dattner, Philip O, Ozuah
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Career calling, ethical sensitivity, and decision-making ability in intensive care nurses: a mediating effect model

Frontiers in Psychology
AimsTo investigate the simultaneous effects of ethical sensitivity and career calling on intensive care nurses’ decision-making ability.MethodsA total 361 intensive care nurses in Hubei Province were selected as survey subjects.
Ke Wang, Yuanyuan Mi, Yanli Wu, Huimin Sun   +3 more
doaj   +1 more source

Decision-making of Early Career Academics: The Possibilities for the Objective Knowledge Growth Framework

Canadian Journal for New Scholars in Education, 2022
Early career academics (ECAs), those who are within the first five years of completing their Ph.D. studies, go through an intense transition process as they deal with career shifts, increasing workload, and job insecurity. As they navigate this new role,
Wenefe Capili-Balbalin, Stephanie Chitpin   +1 more
doaj  

CAREER DECISION-MAKING ATTRIBUTION AND SELF EFFICACY: THE MODERATING ROLE OF EMOTIONAL INTELLIGENCE

Jurnal Psikologi Undip, 2020
It is known that gifted high-school students tend to have difficulty in choosing career due to their wide-range interests and capabilities. In order to successfully making an appropriate career choice, having a high level of career decision making self ...
Rose Mini Agoes Salim, Shahnaz Safitri
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source