Results 111 to 120 of about 705,010 (250)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Future internet enablers for VGI applications

, 2013
This paper presents the authors experiences with the development of mobile Volunteered Geographic Information (VGI) applications in the context of the ENVIROFI project and Future Internet Public Private Partnership (FI-PPP) FP7 research programme.FI-PPP ...
Pielorz, Jasmin, Berre, Arne, Middleton, Stuart, Havlik, Denis, Granell, Carolos, Soriano, Javier, van der Schaaf, Hylke   +6 more
core   +1 more source

Academics’ experiences of work-life balance and work-life conflict in a familialist state: The case of Bosnia and Herzegovina [version 2; peer review: 2 approved]

Open Research Europe
Background This paper explores how women academics in Bosnia and Herzegovina (BiH) navigate work-life conflict and the main strategies they deploy to balance their work and personal lives.
Sara Clavero, Caitriona Delaney
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Who Cares About Fieldwork? A Person‐Centred Framework for a Compassionate Early‐Career Fieldwork Pedagogy

Social Inclusion
The concept of “fieldwork” has been subject to longstanding critique, particularly regarding unequal researcher–participant dynamics, and the extractive colonial legacies that shape knowledge produced in the “field.” Early‐career fieldworkers often ...
Sophie Standen, Andy Harrod
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

What is known about women’s career progression to STEM research leadership in Indonesia? A systematic review

Educational Futures
This article comprises a systematic review of the literature on women leaders’ career progression to STEM (Science, Technology, Engineering, and Mathematics) research leadership in Indonesia published from 2000–2024.
Charalampia Karagianni, Julia Everitt
doaj  

Teaching While Learning: Challenges and Opportunities for Pre-Service Teachers in Addressing Australia’s Teaching Workforce Shortage

Education Sciences
This study examines the experiences of pre-service teachers (PSTs) participating in Australian state-and-territory-specific programs that address teacher workforce shortages in Australia.
Rozi Binte Rahmat, Loretta Bowshall-Freeman, Kerry Bissaker, Siyu Duan, Chris Morrissey, Matthew Winslade, Kathleen Plastow, Catherine Reid, Anne McLeod   +8 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source