Results 221 to 230 of about 6,123,875 (286)

Increasing Lipid Nanoparticle mRNA Copy Number Improves Transfection Potency

open access: yesAdvanced Materials, EarlyView.
As lipid nanoparticle (LNP) systems are the leading platform for in vivo nucleic acid delivery, improving transfection potency of these systems is of considerable interest. In this work, we explored a post‐mixing formulation method involving a two‐step buffer exchange that increased the number of mRNA copies within each LNP while reducing the number of
Yao Zhang   +12 more
wiley   +1 more source

A Critical Call for Mechanistic Investigations of Metal‐Bacteria Interactions

open access: yesAdvanced Materials, EarlyView.
It is well established that the antibacterial properties of metals have tremendous importance for bioengineering applications. What is not as appreciated, however, is the reproducibility crisis in this field's vast literature. In this perspective, we highlight this reproducibility problem, discuss its sources, and suggest solutions towards focused ...
J. Rackwitz   +9 more
wiley   +1 more source

Synthesis of Ti2B2Clx MBenes in Molten Salts From Theoretical and Experimental Perspectives

open access: yesAdvanced Materials, EarlyView.
By integrating a theoretical framework with experiments, Ti2InB2 was selectively etched with ZnCl2 to produce a multilayer (ml) Ti2B2Clx MBene. The In atoms are completely removed, with simultaneous incorporation of chlorine surface terminations. in situ x‐ray diffraction indicates a direct biphasic transformation from Ti2InB2 to ml‐MBene, with no ...
Rodrigo M. Ronchi   +15 more
wiley   +1 more source

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