Results 91 to 100 of about 84,741 (308)
Enhancing professionalism - progressing the career development sector [PDF]
, 2015 Much has changed in the career development sector since the launch of the Careers Profession Task Force report, ‘Towards a Strong Careers Profession’ in 2010.
Neary, Siobhan +2 more
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The Journal for Transdisciplinary Research in Southern Africa, 2019 This study examined school learner views on career guidance processes and outcomes contrasting historically advantaged and disadvantaged schools in the Free State province, South Africa.
Petronella Jonck, Eben Swanepoel
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Peningkatan Kemampuan Perencanaan Karier Peserta Didik Melalui Bimbingan Karier
Teraputik: Jurnal Bimbingan dan KonselingCareer planning is very important for all students before entering the world of work. Therefore all students need to plan their careers well. The purpose of this study was to analyze the improvement of students' career planning abilities through career ...
Wirastiani Binti Yusup
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Challenges to recruitment for the career development sector [PDF]
, 2018 In spring 2018 the Career Development Institute (CDI) together with the International Centre for Guidance Studies (iCeGS) at the University of Derby undertook research with employers in the career development sector to assess current workforce needs ...
Neary, S.
core
The Saudi Experiment with Career Guidance [PDF]
, 2017 Saudi Arabia has recently embarked on an ambitious experiment with career guidance. The country has identified that career guidance offers a range of potential cultural, educational and economic benefits.
Tristram Hooley, Hooley, Tristram
core +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Frontiers in PsychologyIntroductionPrevious studies about the drivers of follower performance focused on leadership, and most followership studies have used a single perspective to investigate this topic from the followers’ lens.
Jing Yu, Jing Yu, Jian Feng
doaj +1 more source