Results 71 to 80 of about 897,722 (306)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Strengthening Career Guidance for New Jersey High School Students [PDF]

open access: yes, 2003
This report is based on the findings of a conference held in October 2003 by the Heldrich Center and the State of New Jersey. The report includes the highlights of major speeches by Heldrich Center director Van Horn, Labor Commissioner Kroll, and ...
Denise Pierson-Balik   +1 more
core  

Effective Policy Frameworks for the Organisation of Career Guidance Services A Review of the Literature [PDF]

open access: yes, 2015
This paper focuses on how public policy shapes career guidance and establishes a system within which individuals can access career support. Governments are critical to career guidance primarily as funders of the activity, but also importantly as ...
Hooley, Tristram   +3 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

A systematic review of research into career guidance policy in the Nordic countries (2008-2022)

open access: yesNordic Journal of Studies in Educational Policy
This article sets out the findings of a systematic review on research into career guidance policy in the Nordic countries between 2008 and 2022. In total 60 papers were reviewed from across the Nordic region.
Tristram Hooley   +7 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

CAREER GUIDANCE SYSTEM

open access: yesIJARCCE
The project aims to develop a career recommendation system for computer engineers, leveraging Python and AI/ML algorithms. It will consider students' academic performance and personal details, culminating in personalized career suggestions and salary estimations.
Adit Kulshreshtha   +3 more
  +4 more sources

Peningkatan Kemampuan Perencanaan Karier Peserta Didik Melalui Bimbingan Karier

open access: yesTeraputik: Jurnal Bimbingan dan Konseling
Career planning is very important for all students before entering the world of work. Therefore all students need to plan their careers well. The purpose of this study was to analyze the improvement of students' career planning abilities through career ...
Wirastiani Binti Yusup
doaj   +1 more source

Statement of client entitlement: good practice guidance: for organisations and practitioners providing career guidance services [PDF]

open access: yes, 2011
"Lifelong Learning UK, (the independent employer-led sector skills council with responsibility for the professional development of staff working in the UK lifelong learning sector) identified a need to develop a UK wide client entitlement statement for

core  

Lifelong guidance policy and practice in the EU [PDF]

open access: yes, 2020
A study on lifelong guidance (LLG) policy and practice in the EU focusing on trends, challenges and opportunities. Lifelong guidance aims to provide career development support for individuals of all ages, at all career stages.
Barnes, Sally-Anne   +4 more
core  

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