Results 71 to 80 of about 1,567,719 (304)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

An examination of university students' perceptions of their secondary career guidance programs [PDF]

open access: yes, 2004
Plan BThe purpose of this study was to examine the perceptions of university undergraduate General Psychology students regarding the effectiveness and content of their high school career guidance programs.
Olson, Elizabeth M.
core  

An exploration of growth strategies for a career guidance organisation in South Africa

open access: yesCogent Education
Effective career guidance remains inaccessible to the youth in South Africa due to the inequalities inherent in the apartheid educational systems. Career guidance significantly influences the course of a young person’s life.
Sihle Shabangu, Favourate Y. Mpofu
doaj   +1 more source

EVALUASI PROGRAM PELAKSANAAN BIMBINGAN KARIR

open access: yesJP (Jurnal Pendidikan), 2019
can reach their maximum self development. The purpose of this study are to describe the context, input, process and product components in guidance career program at SMK Negeri 1 Hiliserangkai Kabupaten Nias.
Aprianus Telaumbanua
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Career Guidance Based on Krumboltz's Social Learning Theory to Develop Students' Career Decisions

open access: yesBisma The Journal of Counseling
Career decisions impact an individual's success and satisfaction in their career. Various factors can hinder teenagers' career decision-making, affecting their future career paths.
Putri Angelina br Ginting   +2 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Peningkatan Kemampuan Perencanaan Karier Peserta Didik Melalui Bimbingan Karier

open access: yesTeraputik: Jurnal Bimbingan dan Konseling
Career planning is very important for all students before entering the world of work. Therefore all students need to plan their careers well. The purpose of this study was to analyze the improvement of students' career planning abilities through career ...
Wirastiani Binti Yusup
doaj   +1 more source

Home - About - Disclaimer - Privacy