Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Interdisciplinary educational intervention to career groups
Background: The quality of life of caregivers is conditioned by several factors: the context of the caregiver, the degree of dependency of the family member, the type of illness, the mediating elements (formal administration and informal support, family ...
Carmen García López +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Assessment of the value of group-based counselling for career construction
This article reports on the change in the career adaptability of participants exposed to an intervention programme characterized by career and self-construction principles compared to the change in participants who participated in standard, traditional ...
Jacobus Gideon Maree +2 more
doaj +1 more source
Career service papers - csp 22/2025 [PDF]
Themen der aktuellen csp sind die Steigerung des Karriereanpassungsvermögens und der Beschäftigungsfähigkeit durch kurze Interventionen, die Auseinandersetzung mit der Frage, wie Emotionen Studierenden helfen Gelerntes längerfristig verfügbar zu halten ...
Wiegand, Dorothee +7 more
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Decision-making style as a predictor of career decision-making status and treatment gains [PDF]
Click on the DOI link to access the article (may not be free).This study investigated the predictability of rational decision- making style on career decision-making status and treatment gains based on a computer-based career intervention.
Mau, Wei-Cheng J.
core +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The role of motivation in a distance career intervention with higher education students [PDF]
Due to the challenges faced by higher education (HE) students in integrating or reintegrating into the workforce, career interventions have gained prominence for their critical role in enhancing students' readiness to tackle professional challenges ...
Almeida, Leandro +3 more
core
Career counseling as an environmental support: Exploring influences on career choice, career decision-making self-efficacy, and career barriers [PDF]
This study was motivated by concerns regarding the difficult academic and career choices facing today’s college students as they navigate higher education and encounter career barriers along their paths.
Makela, Julia P.
core
Developing STEM career identity among Latinx youth: impact of an intervention that integrates STEM learning with individualized learning plans [PDF]
This study reports on the collaboration and impact of an after-school Latinx STEM intervention effort designed to develop both advanced science self-efficacy and career search self-efficacy (Solberg, Nord, & Good, 1994).
Park, C.M. +6 more
core

