Results 51 to 60 of about 264,137 (313)

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Assessing the mediating role of family resilience between caregiver burden and caregiver capacity: a cross-sectional study among Chinese stroke survivors and family caregivers in a real-world setting

BMJ Open
Objectives To investigate the relationships among caregiver burden, family resilience, and caregiver capacity in the care of stroke survivors. We hypothesised that family resilience would mediate the relationship between caregiver burden and caregiver ...
Jingjing Ma, Lu Shi, Yiqing Zhang, Qihang Xu, Qingqing Ge   +4 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Caregiver burden in lung transplantation: A review

JHLT Open
Caregivers play a pivotal role in supporting patients undergoing lung transplant and often experience significant psychological, physical, and financial burdens.
Keerthana Sankar, MD, Anne Johnson, LCSW, Kathryn McRae, LCSW, Reinaldo Rampolla, MD, Nicholas A. Kolaitis, MD, MAS   +4 more
doaj   +1 more source

Association Between Caregivers’ Family Management and Quality of Life in Children with Chronic Disease in Southern Thailand

Patient Preference and Adherence, 2021
Sirikran Sutthisompohn, Kiatkamjorn Kusol School of Nursing, Walailak University, Nakhon Si Thammarat, ThailandCorrespondence: Kiatkamjorn KusolSchool of Nursing, Walailak University, 222 Thaiburi, Thasala District, Nakhon Si Thammarat, ThailandTel +66 ...
Sutthisompohn S, Kusol K
doaj  

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Care burden among Iranian family caregivers of patients with schizophrenia: the predictive role of quality of life and life satisfaction

Frontiers in Psychiatry
IntroductionCaring for patients with schizophrenia poses significant challenges for families. This study examined the relationships between caregiving burden, quality of life, and life satisfaction among family caregivers.MethodsThis cross-sectional ...
Maede Esmaeeli, Seyedmohammad Mirhosseini, Seyedmohammad Mirhosseini, Somaye Minaei-Moghadam, Saeed Ghasempour, Mohammad Hasan Basirinezhad, Hossein Ebrahimi   +6 more
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Analysis of the impact of caregiver training program intervention on frailty in colon cancer patients undergoing postoperative chemotherapy

结直肠肛门外科
[Objectives] To explore the impact of caregiver training program intervention on frailty in colon cancer patients undergoing postoperative chemotherapy.
Nie Tingting, Zhang Wei, Li Yuanyuan, Zhao Tianxue   +3 more
doaj   +1 more source