Results 61 to 70 of about 491,052 (313)

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Caregiver burden in lung transplantation: A review

JHLT Open
Caregivers play a pivotal role in supporting patients undergoing lung transplant and often experience significant psychological, physical, and financial burdens.
Keerthana Sankar, MD, Anne Johnson, LCSW, Kathryn McRae, LCSW, Reinaldo Rampolla, MD, Nicholas A. Kolaitis, MD, MAS   +4 more
doaj   +1 more source

Association Between Caregivers’ Family Management and Quality of Life in Children with Chronic Disease in Southern Thailand

Patient Preference and Adherence, 2021
Sirikran Sutthisompohn, Kiatkamjorn Kusol School of Nursing, Walailak University, Nakhon Si Thammarat, ThailandCorrespondence: Kiatkamjorn KusolSchool of Nursing, Walailak University, 222 Thaiburi, Thasala District, Nakhon Si Thammarat, ThailandTel +66 ...
Sutthisompohn S, Kusol K
doaj  

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Care burden among Iranian family caregivers of patients with schizophrenia: the predictive role of quality of life and life satisfaction

Frontiers in Psychiatry
IntroductionCaring for patients with schizophrenia poses significant challenges for families. This study examined the relationships between caregiving burden, quality of life, and life satisfaction among family caregivers.MethodsThis cross-sectional ...
Maede Esmaeeli, Seyedmohammad Mirhosseini, Seyedmohammad Mirhosseini, Somaye Minaei-Moghadam, Saeed Ghasempour, Mohammad Hasan Basirinezhad, Hossein Ebrahimi   +6 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Analysis of the impact of caregiver training program intervention on frailty in colon cancer patients undergoing postoperative chemotherapy

结直肠肛门外科
[Objectives] To explore the impact of caregiver training program intervention on frailty in colon cancer patients undergoing postoperative chemotherapy.
Nie Tingting, Zhang Wei, Li Yuanyuan, Zhao Tianxue   +3 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

A Systematic Review of Telehealth in Palliative Care: Caregiver Outcomes

, 2016
Objective: Telehealth interventions have proven efficacy in healthcare, but little is known about the results of such interventions in palliative care.
Head, Barbara A., Schapmire, Tara J., Zheng, Yongqiang   +2 more
core  

Hip fracture. Preliminary results supporting significative correlations between the psychological wellbeing of patients and their relative caregivers [PDF]

, 2016
Background and aim. Hip fracture is one of the major causes of loss of self-sufficiency in older patients. The associated caregiving rehabilitation task often falls to the lot of a member of the patient’s family.
Bellanti, G ., Eleuteri, S., Falaschi, P.   +2 more
core