Results 71 to 80 of about 203,179 (264)

Improving Childhood Immunization Service Delivery in Cameroon: A Synthesis of Caregiver Experiences and Recommendations

open access: yesVaccines
Background/Objectives: A “people-centered” approach is one of the core principles of the Immunization Agenda (IA) 2030 and emphasizes the need for services to be organized around the needs and expectations of individuals and the community.
Yauba Saidu   +13 more
doaj   +1 more source

Pengalaman Keluarga dalam Merawat Pasien Pascapasung

open access: yesJurnal Keperawatan Indonesia, 2015
Pasien pasung yang telah pulang dari rumah sakit jiwa (RSJ) oleh keluarga akan berpotensi untuk dipasung kembali. Tujuan penelitian menguraikan pengalaman keluarga dalam merawat pasien pascapasung.
Wahyu Reknoningsih   +2 more
doaj   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller   +14 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

The Interplay of Disability, Depression, Social Support, and Quality of Life in Middle-Aged and Young Couples Affected by Stroke: A Dyadic Path Analysis Using the Actor–Partner Interdependence Mediation Model

open access: yesNursing Reports
Objective: The purpose of this study was to explore the impact of disability on dyadic quality of life (QoL) among stroke survivors and to examine the mediating role of social support in this process. Methods: Outcome measures were collected at four time
Ya-Ting Liu   +10 more
doaj   +1 more source

Effect of Cancer Related Fatigue tTo the Level of Independence of Cancer Patients and Caregiver Stress Level

open access: yesFolia Medica Indonesiana, 2018
Chemotherapy/radiation in cancer patients causes cancer-related fatigue (CRF). It affects the level of independence of patients’ activity of daily living (ADL).
Yesiana Dwi Wahyu Werdani
doaj   +1 more source

Early Recognition of Treatment‐Responsive Rapidly Progressive Dementia: The Modified STAM3mP Score

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Early identification of patients with treatment‐responsive rapidly progressive dementia (RPD) is important as early treatment improves outcomes. The STAM3P score identifies treatment‐responsive RPD using “high risk” presenting features. We optimized performance by adding a time component (i.e., dementia within 3 months) and validated the ...
R. W. van Steenhoven   +16 more
wiley   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Caregiver perceptions of veterinary hospice and palliative care consultations for companion animals

open access: yesHuman-Animal Interactions
Veterinary palliative care encompasses not only the animal but also its caregivers, addressing both medical and emotional needs. Understanding caregivers’ perceptions of veterinary hospice and palliative care (VHPC) consultations is essential for ...
Sofia Mouro
doaj   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

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