Results 51 to 60 of about 1,869,145 (286)
Revista de Psicología, 2021 El objetivo de este estudio es determinar las diferencias que existen en la satisfacción laboral de los trabajadores de una empresa ferroviaria en función de las variables sociodemográficas.
María Fernanda Chocano Córdova +1 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Вестник СибАДИ, 2018 Introduction. The work of a crane - a pipe-laying machine in difficult ground conditions has a significant influence on the process of performing the work and the mode of the machine operation. The unevenness of the microrelief is the main reason for the
R. Y. Sukharev, V. V. Tanskiy
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Science, 2008 In eukaryotic cells, most newly synthesized secretory proteins are first translocated into the endoplasmic reticulum (ER) and transit through organelles that constitute a secretory pathway. However, a fraction of them never reach the desired native state.
Braakman, I., Otsu, M.
openaire +3 more sources
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Business Opportunities for a Ground Effect Vehicle - Case of Canary Islands
Transport and TelecommunicationThe need to decarbonise and reduce pollutant emissions from maritime transport is facilitating the studies of ground effect vehicles. Technical development in recent decade concerning unmanned flights in drones has supported this development.
Otsason Riina +3 more
doaj +1 more source
Bulletin of Kharkiv National University of Internal Affairs, 2023 Unfortunately, the state of law and order on the roads of Ukraine is extremely disappointing, and the sad statistics of road accidents and people injured in them are quite convincing.
O. M. Halkina, A. O. Ivanov
doaj +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
FEBS Open Bio, EarlyView.Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Cooperative transport by small teams of molecular motors [PDF]
, 2006 Molecular motors power directed transport of cargoes within cells. Even if a single motor is sufficient to transport a cargo, motors often cooperate in small teams.
Klumpp, Stefan +2 more
core +2 more sources