Results 81 to 90 of about 2,024,000 (335)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Business Opportunities for a Ground Effect Vehicle - Case of Canary Islands

open access: yesTransport and Telecommunication
The need to decarbonise and reduce pollutant emissions from maritime transport is facilitating the studies of ground effect vehicles. Technical development in recent decade concerning unmanned flights in drones has supported this development.
Otsason Riina   +3 more
doaj   +1 more source

SOME ASPECTS OF AVIATION SERVICE MARKET

open access: yesНаучный вестник МГТУ ГА, 2018
The present day globalization in economy is closely connected with the development of air transport-one of the fastest growing sectors of economy, which provides long-distance transport, primarily to passengers.
A. V. Parkhimovich
doaj   +1 more source

An Optimization Model for Transport-Storage Logistics "An Applied Study" [PDF]

open access: yesMaǧallaẗ Al-Buḥūṯ Al-Mālīyyaẗ wa Al-Tiğāriyyaẗ, 2017
This study is concerned with improving the integrated logistic problem of transport-storage in economic institutions. It provides general proposals to support designers in constructing models and developing computer software to generate optimal logistic ...
Mohamed Mohamed Mohamed Faragallah
doaj   +1 more source

Satisfacción laboral y variables sociodemográficas en los trabajadores de una empresa ferroviaria en la ciudad de Arequipa

open access: yesRevista de Psicología, 2021
El objetivo de este estudio es determinar las diferencias que existen en la satisfacción laboral de los trabajadores de una empresa ferroviaria en función de las variables sociodemográficas.
María Fernanda Chocano Córdova   +1 more
doaj   +1 more source

Properties of tug-of-war model for cargo transport by molecular motors

open access: yes, 2009
Molecular motors are essential components for the biophysical functions of the cell. Our current quantitative understanding of how multiple motors move along a single track is not complete; even though models and theories for single motor chemomechanics ...
J. Howard   +2 more
core   +1 more source

Cooperative transport by small teams of molecular motors [PDF]

open access: yes, 2006
Molecular motors power directed transport of cargoes within cells. Even if a single motor is sufficient to transport a cargo, motors often cooperate in small teams.
Klumpp, Stefan   +2 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

INFLUENCE ANALYSIS OF THE ATTACHMENT COORDINATES RELATING TO THE CARGO OSCILLATIONS ON THE PIPE LAYING CRANE’S BOOM

open access: yesВестник СибАДИ, 2018
Introduction. The work of a crane - a pipe-laying machine in difficult ground conditions has a significant influence on the process of performing the work and the mode of the machine operation. The unevenness of the microrelief is the main reason for the
R. Y. Sukharev, V. V. Tanskiy
doaj   +1 more source

An effector of the Irish potato famine pathogen antagonizes a host autophagy cargo receptor [PDF]

open access: yes, 2016
Plants use autophagy to safeguard against infectious diseases. However, how plant pathogens interfere with autophagy-related processes is unknown. Here, we show that PexRD54, an effector from the Irish potato famine pathogen Phytophthora infestans, binds
Altschul   +48 more
core   +2 more sources

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