Results 41 to 50 of about 107,498 (264)
El nuncio Federico Borromeo y la caída del padre Nithard (1668–69)
El artículo estudia la intervención del nuncio de Clemente IX, Federico Borromeo, como mediador en la crisis política que supuso la salida de la corte y de España del jesuita Everardo Nithard, confesor y favorito de la reina Mariana de Austria, al final
Luis Ribot García
doaj +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Increased healthcare costs in COVID-19 patients with unhealthy habits: The case of smoking
Introduction This study aims to analyze the differences in the prognosis and cost of COVID-19 patients in terms of mortality and occurrence of complications due to tobacco use.
Eva María Andrés Esteban +2 more
doaj +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Las medidas políticas adoptadas por Oliver Cromwell en Irlanda generaron un movimiento migratorio de religiosas que, expulsas de sus conventos, fueron acogidas en congregaciones y conventos castellanos.
Cristina Bravo Lozano
doaj +1 more source
La fundición de Eugui en el Reinado de Carlos II = The Foundry of Eugui in the Reign of Carlos II
El trabajo sintetiza e interpreta lo que sabemos sobre la fundición de Eugui durante el reinado de Carlos II, desde su establecimiento por Aldaz en 1689. Se alude a sus antecedentes, a su producción, a su relación con las necesidades militares de la Monarquía, y con la «hora navarra», y a su significado en la historia de la industria metalúrgica y del ...
openaire +3 more sources
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Reseña del libro de SANZ CAMAÑES, Porfirio, En la periferia del Imperio español. Fidelidad, guerra y supervivencia en el Aragón de Carlos II, Madrid, Sílex ediciones, 2024, 256 pp. ISBN: 978-84-10267-06-0.
Enrique Solano Camón
doaj +1 more source
Nuevas consideraciones sobre los títulos cortesanos de Francisco Rizi
Este artículo presenta nuevos detalles sobre la biografía del pintor español Francisco Rizi a partir de una relectura de fuentes ya conocidas; se establece una nueva fecha de su nombramiento como pintor del Rey y se dan nuevas precisiones sobre su ...
Eduardo Lamas Delgado
doaj +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source

