Results 101 to 110 of about 162,227 (374)

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

L-Carnitine in Drosophila: A Review

Antioxidants, 2020
L-Carnitine is an amino acid derivative that plays a key role in the metabolism of fatty acids, including the shuttling of long-chain fatty acyl CoA to fuel mitochondrial β-oxidation.
Maria Rosaria Carillo, Carla Bertapelle, Filippo Scialò, Mario Siervo, Gianrico Spagnuolo, Michele Simeone, Gianfranco Peluso, Filomena Anna Digilio   +7 more
doaj   +1 more source

Interactive effects of added L-carnitine and chromium picolinate on sow reproductive performance [PDF]

, 2001
A total of 599 sows were used to determine the effects of added L-carnitine and/or chromium picolinate on reproductive performance. Experimental treatments were arranged in a 2 × 2 factorial with main effects of added L-carnitine (0 or 50 ppm) and ...
Dritz, Steven S., Goodband, Robert D., Nelssen, Jim L., Owen, K.Q., Real, D.E., Stoller, S., Tokach, Michael D.   +6 more
core   +2 more sources

Dual Functions of Dietary Rubber Seed Oil Supplementation: Enriching N‐3 Polyunsaturated Fatty Acids and Enhancing Antioxidant Capacity in Pekin Ducks

Animal Research and One Health, EarlyView.
Dietary RSO supplementation improved growth performance, simultaneously enriched n‐3 polyunsaturated fatty acids (n‐3 PUFA), and enhanced antioxidant capacity in Pekin ducks, which suggested that RSO has the potential to be a novel n‐3 PUFA source and an antioxidant for Pekin ducks to generate animal functional foods.
Lei Zhuang, Yongbao Wu, Zitao Zhao, Junting Cao, Yanhong Guo, Zhanyue Wu, Qimeng Wang, Peilong Yang, Sen Wu, Zhiguo Wen, Shuisheng Hou   +10 more
wiley   +1 more source

Exogenous L-Carnitine Promotes Plant Growth and Cell Division by Mitigating Genotoxic Damage of Salt Stress

Scientific Reports, 2019
L-carnitine is a fundamental ammonium compound responsible for energy metabolism in all living organisms. It is an oxidative stress regulator, especially in bacteria and yeast and lipid metabolism in plants.
Signem Oney-Birol
semanticscholar   +1 more source

Overview of Encapsulated Lysine and Methionine and Their Impacts on Transition Cow Performance and Health

Animal Research and One Health, EarlyView.
The transition period in dairy cows, spanning 3 weeks before and after calving, is a critical phase characterized by increased nutrient demands, reduced dry matter intake (DMI), and elevated risk of metabolic disorders such as negative nutrient balance (NNB), lipolysis, proteolysis, and oxidative stress.
Mohammed S. Seleem, Samy A. Elsaadawy, Zhaohai Wu, Lu Ma, Todd R. Callaway, Dengpan Bu   +5 more
wiley   +1 more source

Effects of Dietary Supplements of Pediasure and Carnitine on the Anthropometric Indicesin Children with Acute Lymphoblastic Leukemia under Chemotherapy, in Afzalipour Hospital, Kerman,Iran [PDF]

Journal of Kerman University of Medical Sciences, 2014
Background & Aims: Malnutrition is a common complication of cancer and cancer treatment in children. This occurs in 50% of these patients. Dietary supplements may have a significant effect on the response to treatment,survival, recurrence, mortality, and
A Naderi, F Doustan, A Shahabi Nejad, A Dehghani, M Hayatbakhsh Abbasi   +4 more
doaj  

Effect of Copper on the Mitochondrial Carnitine/Acylcarnitine Carrier Via Interaction with Cys136 and Cys155. Possible Implications in Pathophysiology

Molecules, 2020
The effect of copper on the mitochondrial carnitine/acylcarnitine carrier (CAC) was studied. Transport function was assayed as [3H]carnitine/carnitine antiport in proteoliposomes reconstituted with the native protein extracted from rat liver mitochondria
Nicola Giangregorio, Annamaria Tonazzi, Lara Console, Mario Prejanò, Tiziana Marino, Nino Russo, Cesare Indiveri   +6 more
doaj   +1 more source

Role of L-carnitine in female infertility

Reproductive Biology and Endocrinology, 2018
BackgroundL-carnitine (LC), and its acetylated form, acetyl L-carnitine (ALC), have immense functional capabilities to regulate the oxidative and metabolic status of the female reproductive system. The vulnerability of this system to free radicals demand
A. Agarwal, P. Sengupta, D. Durairajanayagam   +2 more
semanticscholar   +1 more source

Spermidine Reproduces the Anti‐Inflammatory Effects of Intermittent Fasting and Prevents Urate and Calcium Pyrophosphate Crystal‐Induced Inflammation

Arthritis &Rheumatology, EarlyView.
Objective Gout caused by the formation of monosodium urate (MSU) crystals and calcium pyrophosphate (CPP) deposition disease are two major types of microcrystalline pathologies in adults. They are responsible for recurrent flares that rely on interleukin (IL) 1β via activation of the NLRP3 inflammasome.
Chinh Nghia Pham, Florence Castelli, Flora Finet, Charles Leroy, Céline Chollet, Twinu W. Chirayath, Subhalaxmi Moitra, Mylène Zarka, Agnès Ostertag, François Brial, Christèle Combes, Augustin Latourte, Thomas Bardin, François Fenaille, Pascal Richette, Hang Korng Ea   +15 more
wiley   +1 more source