Results 111 to 120 of about 133,759 (327)

Oleoylethanolamide regulates intestinal stem cell activity and villus size via PPARα signaling pathway

open access: yesiMetaOmics, EarlyView.
First use of a natural swine model with lipid metabolism to directly link lipid differences to a quantifiable intestinal villus height phenotype. Identified the phospholipid‐derived oleoylethanolamide, rather than canonical fatty acids, as the endogenous primary ligand that activates peroxisome proliferator‐activated receptors α (PPARα) to enlarge ...
Qianqian Wang   +9 more
wiley   +1 more source

Effects of negative energy balance on liver gene and protein expression during the early postpartum period and its impacts on dairy cow fertility [PDF]

open access: yes, 2007
End of project reportNegative energy balance (NEB) is a severe metabolic affecting high yielding dairy cows early post partum with both concurrent and latent negative effects on cow fertility as well as on milk production and cow health.
Diskin, Michael G.   +9 more
core  

Carnitine is necessary to maintain the phenotype and function of brown adipose tissue [PDF]

open access: bronze, 2011
Kiyokazu Ozaki   +4 more
openalex   +1 more source

Risk factors for carnitine deficiency in critically ill adults: A descriptive cross‐sectional study

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Critical illness is a risk factor for carnitine deficiency. Carnitine deficiency may result in serious medical complications and poor clinical outcomes. This study aimed to identify the prevalence and potential predictors of carnitine deficiency.
Jennifer Gordon   +6 more
wiley   +1 more source

Simultaneous Analysis of L-Carnitine and Acetyl-L-Carnitine in Food Samples by Hydrophilic Interaction Nano-Liquid Chromatography

open access: yesMethods and Protocols
L-Carnitine (L-CAR) and acetyl-L-carnitine (Acetyl L-CAR) are the essential cofactor compounds in lipid metabolism and are used in the treatment of various diseases.
Cemil Aydoğan   +2 more
doaj   +1 more source

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira   +9 more
wiley   +1 more source

Effects of Pemafibrate on Serum Carnitine and Plasma Myostatin in Patients With Metabolic Dysfunction Associated Steatotic Liver Disease

open access: yesJCSM Communications
Background Pemafibrate, a selective peroxisome proliferator‐activated receptor alpha (PPARα) modulator (SPPARMα), has positive effects on liver‐related markers (e.g., liver stiffness determined by magnetic resonance elastography and alanine ...
Ryohei Tanigawa   +7 more
doaj   +1 more source

Dysfunction of the carnitine cycle in tumor progression

open access: yesHeliyon
The carnitine cycle is responsible for the transport of cytoplasmic fatty acids to the mitochondria for subsequent β-oxidation to maintain intracellular energy homeostasis.
Xiangjun Wang   +3 more
doaj   +1 more source

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