Results 131 to 140 of about 162,227 (374)

PREVENTION OF HEPATOTOXICITY OF VALPROIC ACID WITH CONCOMITANT SUPPLEMENT OF CARNITINE: AN EXPERIMENTAL STUDY IN ALBINO RATS

Gomal Journal of Medical Sciences, 2014
Background: Valproic acid is an antiepileptic drug which may cause carnitine deficiency and subsequently hepatotoxicity in the form of necrosis and steatosis.
Syed Khanzada Khan, Shahida Tasleem, Naila Ismail, Purdil Khan, Kazi Abdul Shakoor   +4 more
doaj  

Functional and molecular studies in primary carnitine deficiency

Human Mutation, 2017
Primary carnitine deficiency is caused by a defect in the OCTN2 carnitine transporter encoded by the SLC22A5 gene. It can cause hypoketotic hypoglycemia or cardiomyopathy in children, and sudden death in children and adults.
Marta Frigeni, B. Balakrishnan, Xue Yin, F. Calderon, R. Mao, M. Pasquali, N. Longo   +6 more
semanticscholar   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, EarlyView.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source

L-carnitine use as a trigger for the onset of Kleine-Levin syndrome: A case presentation (eng)

, 2022
Ferhat Yaylacı, Önder Küçük, Handan Özek Erkuran   +2 more
openalex   +1 more source

LTE: Does caffeine truly raise muscle carnitine in humans? [PDF]

, 2023
Dumitru Constantin‐Teodosiu
openalex   +1 more source

Maintenance of Carnitine Homeostasis as a Therapeutic Strategy to Attenuate Cisplatin‐Induced Acute Kidney Injury

Food Frontiers, EarlyView.
ABSTRACT Acute kidney injury (AKI) has emerged as a significant global public health concern due to its high morbidity and mortality rates. Cisplatin, a highly effective and widely used chemotherapeutic agent, is often limited in clinical application by its nephrotoxicity, particularly AKI.
Mingkang Zhang, Yazhi Wang, Xiujuan Wang, Yan Zhou, Yanrong Ma, Xin'an Wu   +5 more
wiley   +1 more source

l-Carnitine Supplementation in Older Women. A Pilot Study on Aging Skeletal Muscle Mass and Function

Nutrients, 2018
Skeletal muscle wasting, associated with aging, may be regulated by the inflammatory cytokines as well as by insulin-like growth factor 1 (IGF-1). l-carnitine possesses anti-inflammatory properties and increases plasma IGF-1 concentration, leading to the
A. Sawicka, D. Hartmane, P. Lipińska, E. Wójtowicz, W. Lysiak-Szydlowska, R. Olek   +5 more
semanticscholar   +1 more source

Plasma TMAO Concentrations and Gut Microbiota Composition in Subjects with and Without Metabolic Syndrome: Results from Pilot Study

Metabolites
Background/Objectives: Trimethylamine N-oxide (TMAO) is a gut microbiota-dependent metabolite considered as a risk metabolite for various non-communicable diseases.
Mohammed E. Hefni, Cornelia M. Witthöft, Patrik Hellström, Ingegerd Johansson, Anders Esberg   +4 more
doaj   +1 more source

Carnitine [PDF]

Advances in Nutrition, 2014
Jack, Odle, Sean H, Adams, Jerry, Vockley   +2 more
openaire   +2 more sources

The Regulatory Role of Exogenous Carnitine Applications in Lipid Metabolism, Mitochondrial Respiration, and Germination in Maize Seeds (Zea mays L.)

Life
The present study aimed to investigate the effects of exogenous carnitine treatments on maize seed germination by stimulating lipid metabolism and regulating the mitochondrial respiratory pathway.
Hulya Turk, Mucip Genisel, Rahmi Dumlupinar   +2 more
doaj   +1 more source