Results 161 to 170 of about 135,428 (332)
AAV9-TAZ gene replacement ameliorates cardiac TMT proteomic profiles in a mouse model of Barth syndrome [PDF]
, 2019 Byrne, Barry J. +6 more
core +2 more sources
The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes
The FEBS Journal, EarlyView.Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova +12 more
wiley +1 more source
Elucidation of an anaerobic pathway for metabolism of L-carnitine-derived γ-butyrobetaine to trimethylamine in human gut bacteria [PDF]
, 2021 Lauren J. Rajakovich +3 more
openalex +1 more source
Journal of Animal Physiology and Animal Nutrition, EarlyView.ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall +4 more
wiley +1 more source
L-carnitine in metabolic dysfunction-associated steatotic liver disease: mechanisms and therapeutic potential. [PDF]
Front NutrChen C +10 more
europepmc +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet +8 more
wiley +1 more source
Effects of L-carnitine and Ginkgo biloba on Pentylentetrazol-induced liver damage and oxidative stress in rats. [PDF]
, 2016 Reda M. Fekry +3 more
openalex +1 more source
Obesity Reviews, EarlyView.ABSTRACT Background Gut microbiota‐derived metabolites are emerging as potential mediators between obesity and cardiometabolic conditions. While weight loss interventions modify microbiota composition, their effects on systemic microbial metabolites remain unclear.
Fernando Q. Iorra +5 more
wiley +1 more source
Effect of L-Carnitine on Blood Lipid Composition in Atherosclerotic Rats.
, 1994 A. Dayanandan +3 more
openalex +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Placental mitochondrial adaptation to gestational hypoxia. Hypoxic pregnancy in sheep increases placental insulin like growth factor 2 (IGF2) signalling (1), which is associated with a shift in capacity away from β‐oxidation (2) and complex I‐mediated respiration (3), while maintaining total oxidative phosphorylation capacity (4).
Wen Tong +18 more
wiley +1 more source