Results 11 to 20 of about 67,090 (139)
Serum metabolic alterations in peritoneal dialysis patients with excessive daytime sleepiness
Renal Failure, 2023 Excessive daytime sleepiness (EDS) is associated with quality of life and all-cause mortality in the end-stage renal disease population. This study aims to identify biomarkers and reveal the underlying mechanisms of EDS in peritoneal dialysis (PD ...
Wei Chen +8 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021 Background The molecular mechanisms involved in atrial fibrillation are not well known. We used plasma metabolomics to investigate if we could identify novel biomarkers and pathophysiological pathways of incident atrial fibrillation.
Lars Lind +7 more
doaj +1 more source
Valproic-induced Fanconi syndrome: Clinical features, risk factors, diagnosis and management
Frontiers in Medicine, 2022 ObjectiveAlthough Fanconi syndrome (FS) induced by valproate (VPA) has occasionally been reported, the detailed clinical features of the disease remain unclear.
Chunjiang Wang +4 more
doaj +1 more source
The pathophysiology of leg cramping during dialysis and the use of carnitine in its treatment
Physiological Reports, 2021 Leg cramping is a common side effect of hemodialysis, and this is frequently treated by the administration of carnitine, but this is not effective in every patient. Alkalosis is a key component of the etiology of leg cramping during hemodialysis sessions.
Akira Takahashi
doaj +1 more source
Carnitine Inborn Errors of Metabolism
Molecules, 2019 Carnitine plays essential roles in intermediary metabolism. In non-vegetarians, most of carnitine sources (~75%) are obtained from diet whereas endogenous synthesis accounts for around 25%.
Mohammed Almannai +2 more
doaj +1 more source
Molecules, 2021 Carnitine insufficiency is reported in type 1 diabetes mellitus. To determine whether this is accompanied by defects in biosynthesis and/or renal uptake, liver and kidney were obtained from male Sprague-Dawley rats with streptozotocin-induced diabetes ...
Aman Upadhyay +2 more
doaj +1 more source
l-carnitine in critically ill patients—a case series study
Renal Replacement Therapy, 2018 Background l-carnitine is essential for lipid metabolism, and lack of l-carnitine intake and loss by treatments lead to carnitine depletion causing muscle weakness, anemia, and immune dysfunction.
Takehiko Oami +6 more
doaj +1 more source
Frontiers in Nutrition, 2022 Depression has become one of the most common mental diseases in the world, but the understanding of its pathogenesis, diagnosis and treatments remains insufficient.
Ting Liu +12 more
doaj +1 more source
Caffeine ingestion stimulates plasma carnitine clearance in humans
Physiological Reports, 2023 Increasing skeletal muscle carnitine content can manipulate fuel metabolism and improve exercise performance. Intravenous insulin infusion during hypercarnitinemia increases plasma carnitine clearance and Na+‐dependent muscle carnitine accretion, likely ...
Benjamin T. Wall +3 more
doaj +1 more source
Effects of Co-Administration of Bone Marrow Stromal Cells and L-Carnitine on The Recovery of Damaged Ovaries by Performing Chemotherapy Model in Rat [PDF]
International Journal of Fertility and Sterility, 2019 Background L-carnitine (Lc) as a type of flavonoid antioxidants and bone marrow stromal cells (BMSCs) as a type of mesenchymal stem cells may recover damaged ovaries.
Sam Zarbakhsh +6 more
doaj +1 more source