Results 241 to 250 of about 133,759 (327)

<b>Gut‒heart axis: emerging therapies targeting trimethylamine</b> <b>N-oxide production</b>. [PDF]

Gut Microbes
Torres ER, Wilcox J, Tang WHW.
europepmc   +1 more source

A Human Model of Oligodendrocyte Development Shows MCL‐1 Influences Oligodendrocyte Morphogenesis

Glia, Volume 74, Issue 2, February 2026.
A unified model of oligodendrocyte differentiation from human embryonic stem cells revealed that MCL‐1 is critical for regulating the expression of oligodendrocyte‐related genes and the morphogenesis of myelinating oligodendrocytes. ABSTRACT Oligodendrocytes are the myelinating cells of the central nervous system.
Melanie Gil, Marina R. Hanna, Vivian Gama   +2 more
wiley   +1 more source

Intestinal microbiota contributes to the heterogeneity of fat deposition by promoting mitochondrial fatty acid β-oxidation. [PDF]

Gut Microbes
Li L, Zhou N, Wang Z, Wang T, Wang Y, Qiao F, Du ZY, Zhang ML.   +7 more
europepmc   +1 more source

Carnitine [PDF]

, 2020
openaire   +1 more source

Distinct Metabolomic Alterations Are Associated With Physical Function, Weight Loss, and Muscle Mass in Men With Cancer

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Treatments for cancer cachexia, defined as involuntary weight and muscle mass loss leading to significant functional impairment, remain unavailable partly due to insufficient improvement of clinically meaningful outcomes in current trials.
Lindsey J. Anderson, Lu Xia, Haiming Kerr, Marin Cabrera, Fabien Chu, Jaqueline Rose, Peter C. Wu, Atreya Dash, Sina A. Gharib, Jose M. Garcia   +9 more
wiley   +1 more source

Oral octanoylcarnitine alleviates exercise intolerance in mouse models of long-chain fatty acid oxidation disorders. [PDF]

JCI Insight
Solo KJ, Zhang Y, Bharathi SS, Zhang BB, Richert AC, Schmidt AV, Van't Land C, D'Annibale O, Wood TC, Goetzman ES.   +9 more
europepmc   +1 more source

Tumor‐Associated Macrophages as Therapeutic Targets: Deciphering Interaction Networks and Advancing Clinical Translation

MedComm, Volume 7, Issue 2, February 2026.
Tumor‐associated macrophages are the most abundant immune cells in the tumor microenvironment, driving malignant progression and treatment resistance. This review summarizes the protumor mechanisms of TAMs (including phagocytosis modulation, metabolic reprogramming, exosomal communication, and immune interactions), evaluates three major strategies ...
Wurihan Bao, Xiaojie Qu, Yiqi Wang, Dan Huang, Huiling Zhang, Mingyuan Dong, Han Sun, Zhaogang Yang, Xuefeng Li   +8 more
wiley   +1 more source

Mechanical Stimulation Induces Yap Mediated OCTN2 Transcription to Enhance Carnitine Metabolism in Sarcopenia. [PDF]

J Cachexia Sarcopenia Muscle
Lu Y, Bai Y, Li W, Zhou Z, Lai H, Hu X, Yang T, Wang C, Chen Y, Gan K, Li K, Ma H, Shen L, He D.   +13 more
europepmc   +1 more source

Changes in Metabolites and Microbial Communities in Follicular Fluid Associated With Ovarian Function in Patients With Polycystic Ovary Syndrome

MedComm, Volume 7, Issue 2, February 2026.
Based on the integrated analysis of follicular fluid metabolites and microbial communities in patients with PCOS, this study reveals significant dysregulation in the follicular microenvironment. Key metabolites including D‐glucose and 25‐hydroxycholesterol show marked alterations, while microbial communities such as Alicyclobacillus and Terrimonas ...
Manfei Si, Sen Yan, Shu Ding, Rui Liu, Xianglei Xiong, Jie Qiao, Xinyu Qi   +6 more
wiley   +1 more source

Ammonium Hydroxide Enhancement of Dietary Protein in High-Fat Diets Modulates Liver Metabolism Signaling in a Sex- and Age-Dependent Manner in C3H/HeJ Mice. [PDF]

Int J Mol Sci
Barr BR, Subramaniyan I, Li L, Levitt DE, Gollahon LS.   +4 more
europepmc   +1 more source