Results 31 to 40 of about 162,227 (374)

Carnitine and Depression

Frontiers in Nutrition, 2022
Depression has become one of the most common mental diseases in the world, but the understanding of its pathogenesis, diagnosis and treatments remains insufficient.
Ting Liu, Ting Liu, Kunhong Deng, Ying Xue, Ying Xue, Rui Yang, Rui Yang, Rong Yang, Rong Yang, Zhicheng Gong, Zhicheng Gong, Mimi Tang, Mimi Tang   +12 more
doaj   +1 more source

Effects of Co-Administration of Bone Marrow Stromal Cells and L-Carnitine on The Recovery of Damaged Ovaries by Performing Chemotherapy Model in Rat [PDF]

International Journal of Fertility and Sterility, 2019
Background L-carnitine (Lc) as a type of flavonoid antioxidants and bone marrow stromal cells (BMSCs) as a type of mesenchymal stem cells may recover damaged ovaries.
Sam Zarbakhsh, Robabeh Safari, Hamid Reza Sameni, Behpour Yousefi, Manouchehr Safari, Nasrin Khanmohammadi, Parisa Hayat   +6 more
doaj   +1 more source

Inulin-Based Polymeric Micelles Functionalized with Ocular Permeation Enhancers: Improvement of Dexamethasone Permeation/Penetration through Bovine Corneas

Pharmaceutics, 2021
Ophthalmic drug delivery is still a challenge due to the protective barriers of the eye. A common strategy to promote drug absorption is the use of ocular permeation enhancers, while an innovative approach is the use of polymeric micelles. In the present
Giulia Di Prima, Mariano Licciardi, Flavia Bongiovì, Giovanna Pitarresi, Gaetano Giammona   +4 more
doaj   +1 more source

Na+-dependent and Na+-independent betaine transport across the apical membrane of rat renal epithelium [PDF]

, 2015
The low renal excretion of betaine indicates that the kidney efficiently reabsorbs the betaine filtered by the glomeruli but the mechanisms involved in such a process have been scarcely investigated.
Calonge Castrillo, María Luisa, Cano Rodríguez, María Mercedes, Ilundáin Larrañeta, María Anunciación Ana   +2 more
core   +1 more source

Detection of Early Onset Carnitine Palmitoyltransferase II Deficiency by Newborn Screening: Should CPT II Deficiency Be a Primary Disease Target?

International Journal of Neonatal Screening, 2021
Early-onset carnitine palmitoyltransferase II deficiency (CPT II deficiency) (OMIM 600650) can result in severe outcomes, which are often fatal in the neonatal to infantile period.
Rachel Mador-House, Zaiping Liu, Sarah Dyack   +2 more
doaj   +1 more source

The Importance of the Fatty Acid Transporter L-Carnitine in Non-Alcoholic Fatty Liver Disease (NAFLD)

Nutrients, 2020
L-carnitine transports fatty acids into the mitochondria for oxidation and also buffers excess acetyl-CoA away from the mitochondria. Thus, L-carnitine may play a key role in maintaining liver function, by its effect on lipid metabolism.
D. Savić, L. Hodson, S. Neubauer, M. Pavlides   +3 more
semanticscholar   +1 more source

L- and DL-carnitine induce tetanic fade in rat neuromuscular preparation

Brazilian Journal of Medical and Biological Research, 2003
Carnitine, a structurally choline-like metabolite, has been used to increase athletic performance, although its effects on neuromuscular transmission have not been investigated. It is present in skeletal muscle and its plasma levels are about 30 to 90 µM.
G. Lopes, R.B. Bazotte, R. Curi, W. Alves-Do-Prado   +3 more
doaj   +1 more source

L-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans

Journal of Clinical Investigation, 2018
BACKGROUND.L-Carnitine, an abundant nutrient in red meat, accelerates atherosclerosis in mice via gut microbiota–dependent formation of trimethylamine (TMA) and trimethylamine N-oxide (TMAO) via a multistep pathway involving an atherogenic intermediate, &
Betzabe Robert A. Koeth, Rachel Lam-Galvez, Jennifer Kirsop, Zeneng Wang, B. Levison, Xiaodong Gu, Matthew F. Copeland, David Bartlett, David B. Cody, H. J. Dai, Miranda K. Culley, Xinmin S. Li, Xiaoming Fu, Yuping Wu, Lin Li, J. DiDonato, W. H Wilson Tang, Jose Carlos, S. L. Hazen, Betzabe Rachel, Lam-Galvez, W. H. Wilson Tang   +21 more
semanticscholar   +1 more source

Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled study [PDF]

, 2018
Since sperm require high energy levels to perform their specialised function, it is vital that essential nutrients are available for spermatozoa when they develop, capacitate and acquire motility.
Agarwal, A., Antonini, G., Busetto, G. M., De Berardinis, E., Del Giudice, F., Gentile, V., Micic, S., Ragonesi, G., Virmani, A.   +8 more
core   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source