Results 181 to 190 of about 9,220 (223)
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Experientia, 1981
Carnosine levels were determined in chick erythrocytes (2510 nmoles/g cells) and plasma from chick (27 nmoles/ml),rat and rabbit. Carnosine was also measured in rabbit reticulocyte-rich blood (105 nmoles/g cells), normal blood (18 nmoles/g cells) and in bone marrow.
J E, Seely, F D, Marshall
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Carnosine levels were determined in chick erythrocytes (2510 nmoles/g cells) and plasma from chick (27 nmoles/ml),rat and rabbit. Carnosine was also measured in rabbit reticulocyte-rich blood (105 nmoles/g cells), normal blood (18 nmoles/g cells) and in bone marrow.
J E, Seely, F D, Marshall
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Neurochemical Research, 1977
The amount and specificity of binding ofL-carnosine (β-alanyl-L-histidine) by crude soluble and particulate fractions of several tissues were investigated with proton magnetic resonance ((1)HMR) spectrometry. It was found that the particulate fraction of only nasal olfactory mucosa exhibited a specific binding requiring a particular orientation of the ...
C E, Brown +4 more
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The amount and specificity of binding ofL-carnosine (β-alanyl-L-histidine) by crude soluble and particulate fractions of several tissues were investigated with proton magnetic resonance ((1)HMR) spectrometry. It was found that the particulate fraction of only nasal olfactory mucosa exhibited a specific binding requiring a particular orientation of the ...
C E, Brown +4 more
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Carnosine treatment largely prevents alterations of renal carnosine metabolism in diabetic mice
Amino Acids, 2011Recently, we identified an allelic variant of human carnosinase 1 (CN1) that results in increased enzyme activity and is associated with susceptibility for diabetic nephropathy in humans. Investigations in diabetic (db/db) mice showed that carnosine ameliorates glucose metabolism effectively.
Verena Peters +5 more
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Plasma carnosine, but not muscle carnosine, attenuates high-fat diet-induced metabolic stress
Applied Physiology, Nutrition, and Metabolism, 2015There is growing in vivo evidence that the dipeptide carnosine has protective effects in metabolic diseases. A critical unanswered question is whether its site of action is tissues or plasma. This was investigated using oral carnosine versus β-alanine supplementation in a high-fat diet rat model.
S. Stegen +10 more
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Brain Research, 1979
The dipeptide, carnosine, its synthetic enzyme, carnosine synthetase, and its degradative enzyme, carnosinase, appear to be localized in the cytosol of mouse olfactory bulb and epithelium. Mouse olfactory bulbs and epithelium were prelabeled in vivo with [3H]carnosine following intranasal irrigation with [3H]beta-alanine.
J W, Harding, J V, O'Fallon
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The dipeptide, carnosine, its synthetic enzyme, carnosine synthetase, and its degradative enzyme, carnosinase, appear to be localized in the cytosol of mouse olfactory bulb and epithelium. Mouse olfactory bulbs and epithelium were prelabeled in vivo with [3H]carnosine following intranasal irrigation with [3H]beta-alanine.
J W, Harding, J V, O'Fallon
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Carnosine, carnitine, and Vladimir Gulevich
Journal of Chemical Education, 1974Vladimir Gulevich was a distinguished biochemist who was responsible for the discovery of several biologically important bases and who inspired some extremely capable students and associated to con...
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Carnosine and Cognitive Deficits
2015Carnosine (β-alanyl- l -histidine) is a natural dipeptide widely and abundantly distributed in excitable tissues of several animals. Although its physiological role has not been completely understood yet, many beneficial actions have been attributed to carnosine, such as being an antioxidant, antiglycating and ion-chelating agent, a wound-healing ...
Bellia F +2 more
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Carnosine and Carnosinase in Rat Tissue
Nature, 1957PAPER chromatography has been used for obtaining a qualitative picture of the distribution of carnosine and ‘carnosinase’ in the albino rat.
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