Results 91 to 100 of about 674,288 (407)
Ulceration and carotid artery disease. [PDF]
Stroke, 1988 L'importance de l'ulceration des plaques carotidiennes comme cause de symptomes ischemiques cerebraux reste controversee. Une ulceration est souvent observee dans les plaques homolaterales aux symptomes ischemiques mais habituellement en association a une stenose importante.
openaire +3 more sources
Advanced Science, EarlyView.Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang +6 more
wiley +1 more source
High fat diet attenuates the anticontractile activity of aortic PVAT via a mechanism involving AMPK and reduced adiponectin secretion [PDF]
, 2018 Background and aim: Perivascular adipose tissue (PVAT) positively regulates vascular function through production of factors such as adiponectin but this effect is attenuated in obesity.
Alganga, Husam +9 more
core +2 more sources
Advanced Science, EarlyView.This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen +12 more
wiley +1 more source
Metabolites, 2016 Adipokines are important regulators of several processes, including inflammation and atherosclerosis. In patients with systemic autoimmune diseases, atherosclerosis is accelerated with higher cardiovascular morbidity and mortality.
Nahoko Tanaka +4 more
doaj +1 more source
PERIPHERAL ARTERY DISEASE, SYMPTOMS AND CAROTID ARTERY DISEASE
Journal of the American College of Cardiology, 2012 Peripheral arterial disease (PAD) patients are at an increased risk of disease in other vascular territories. The relationship between PAD and carotid artery disease is unknown. A prospective database was used of over 3.5 million U.S.
Mark A. Adelman +5 more
openaire +2 more sources
Carotid intima-media thickness as a biomarker of subclinical atherosclerosis.
Swiss medical weekly, 2012 Intima-media thickness of the carotid artery (CIMT) and its increase is associated with several cardiovascular risk factors and manifest cardiovascular diseases. CIMT is suggested to be an important biomarker of subclinical atherosclerosis.
M. Bauer +5 more
semanticscholar +1 more source
The roles of endoglin gene in cerebrovascular diseases. [PDF]
, 2017 Endoglin (ENG, also known as CD105) is a transforming growth factor β (TGFβ) associated receptor and is required for both vasculogenesis and angiogenesis.
Ma, Li, Su, Hua, Zhang, Rui, Zhu, Wan
core +2 more sources
ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy
Advanced Science, EarlyView.Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie +11 more
wiley +1 more source
Advances in endovascular therapy for ischemic cerebrovascular diseases
Chronic Diseases and Translational Medicine, 2016 Endovascular therapy for ischemic cerebrovascular diseases has developed rapidly in recent years. The latest clinical trials of acute ischemic stroke have shown promising results with the continued advancement of concepts, techniques, and materials ...
Jun Lu, Daming Wang
doaj +1 more source