HIF-2α is essential for carotid body development and function
Mammalian adaptation to oxygen flux occurs at many levels, from shifts in cellular metabolism to physiological adaptations facilitated by the sympathetic nervous system and carotid body (CB).
David Macías+5 more
semanticscholar +1 more source
Bilateral carotid body tumor case: A novel preoperative management
Paragangliomas are rare neuroendocrine neoplasms. The most common form of these tumors in head and neck are non-functional carotid body tumors. These neoplasms may present an extensive growth and compromise vital neurovascular structures in the neck ...
Alberto Moscona-Nissan+6 more
doaj
Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors [PDF]
Airway neuroepithelial bodies sense changes in inspired O2, whereas arterial O2 levels are monitored primarily by the carotid body. Both respond to hypoxia by initiating corrective cardiorespiratory reflexes, thereby optimising gas exchange in the face ...
Kemp, P.J., Peers, C.
core +4 more sources
Metformin for non-diabetic patients with coronary heart disease (the CAMERA study): a randomised controlled trial [PDF]
<br>Background: Metformin reduces cardiovascular risk in patients with type 2 diabetes seemingly independent of lowering blood glucose concentration. We assessed the cardiovascular effects of metformin in individuals without type 2 diabetes.</br&
Eddy+33 more
core +5 more sources
Association between serum Mg2+ concentrations and cardiovascular organ damage in a cohort of adult subjects [PDF]
Magnesium (Mg2+) levels are associated with insulin resistance, hypertension, atherosclerosis, and type 2 diabetes (T2DM). We evaluated the clinical utility of physiological Mg2+ in assessing subclinical cardiovascular organ damage including increased ...
Andreozzi, F.+12 more
core +1 more source
Hypoxic regulation of ion channel function and expression [PDF]
Acute hypoxia regulates the activity of specific ion channels in a rapid and reversible manner. Such effects underlie appropriate cellular responses to hypoxia which are designed to initiate cardiorespiratory reflexes and contribute importantly to other ...
Peers, C.
core +1 more source
Augmented reflex responses from peripheral chemoreceptors, which are mainly localized in the carotid bodies (CBs), characterize patients with systolic heart failure and contribute to adrenergic hyperactivation.
P. Niewiński+13 more
semanticscholar +1 more source
Fine-needle aspiration cytology diagnosis of paraganglioma (carotid body tumor)
A case of carotid body tumor was diagnosed based on fine-needle aspiration cytology (FNAC) in 22-year-old female who presented with a mass in the right lower cervical region. Provisional diagnosis was made as metastatic deposits.
Kalyani Dukkipati+1 more
doaj +1 more source
Multiple paragangliomas involving carotid body and vagal region
Paragangliomas are rare neuroendocrine tumors also known to occur in the head-and-neck regions and generally involve the carotid body or vagal region. Till date, only a single study has reported the occurrence of paragangliomas involving both the carotid
Jaimanti Bakshi+3 more
doaj +1 more source
Association between adiposity and systemic atherosclerosis: a protocol of a cross-sectional autopsy study. [PDF]
IntroductionAdiposity has been associated with atherosclerosis in clinical studies. However, few autopsy studies have investigated this association, and they had only examined the coronary artery disease. Moreover, most studies had small sample sizes and
Campos, Fernanda Marinho+11 more
core +2 more sources