Results 121 to 130 of about 75,137 (261)

Nasopharyngeal Carriage of Neisseria meningitidis in 181 Hajj and Umrah Pilgrims in Türkiye: Pre- and Post-Travel Prevalence and Serogroup Distribution n. [PDF]

Med Sci Monit
Saglan Y, Bilge U, Saglan R, Kılıc O, Dinleyici M, Balcıoglu H, Dinleyici EC.   +6 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Meningococcal carriage in UK university students post-pandemic: evidence for MenACWY vaccine impact and ongoing genogroup B risk. [PDF]

Front Public Health
Harvey-Cowlishaw T, Wartnaby S, Trujillo-Mendoza J, Clark JL, Lekshmi A, Clark SA, Royal S, Bayliss CD, Turner DPJ, Oldfield NJ.   +9 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Carriage rate of CPE, ESBL-producing coliforms and MRSA in community settings in Suriname. [PDF]

JAC Antimicrob Resist
Rozemond CM, Adhin MR, Williams W, De Greeff SC, Van Duijkeren E, Vreden SG, Mawie FT, Ijzerman E, Hordijk J, Van Dissel JT.   +9 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A Multidesign Study of 4CMenB Vaccine Effectiveness and Impact on Meningococcal Carriage and Gonorrhea in Northern Territory Adolescents and Young People. [PDF]

Open Forum Infect Dis
McMillan M, Wang B, Krause V, Greenwood-Smith B, Webby R, Chen J, Baird R, Gerrell J, Prince K, Whop L, Giles L, Bednarz J, Kaldor J, D'Antoine H, Binks M, Andrews R, Richmond P, Macartney K, Whiley D, Lawrence A, Petousis-Harris H, Ward J, Marshall H.   +22 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Prevalence, Serotype Distribution, and Risk Factors Associated With <i>Streptococcus pneumoniae</i> Carriage in Older Adults in Denmark, 2019-2022. [PDF]

Open Forum Infect Dis
Tinggaard M, Slotved HC, Petersen RF, Hovmand N, Benfield T.   +4 more
europepmc   +1 more source