Results 141 to 150 of about 75,137 (261)

Carriage epidemiology of Moraxella catarrhalis in an all-age community cohort between 2016 and 2018. [PDF]

Access Microbiol
Morris DE, Lister AJJ, Cleary DW, Clarke SC.   +3 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Pneumococcal transmission is driven by TNFR2+ regulatory T-cells. [PDF]

Front Immunol
Beentjes D, Murray J, French N, Vipond C, Xu R, Kadioglu A.   +5 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Nasal carriage of <i>Staphylococcus aureus</i> and hygiene practices among food handlers in Skopje, North Macedonia. [PDF]

Arh Hig Rada Toksikol
Bukovetz J, Todorovski J, Zendeli G, Mijakoski D, Kočubovski M, Kotevska V, Spiroski I.   +6 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

<i>Salmonella</i> bloodstream infection and concurrent intestinal colonization in children with severe acute malnutrition in Niger. [PDF]

Microb Genom
Sands K, Campillo R, Boostrom I, Lai G, Lankapalli AK, Cook K, Hassan B, Portal EA, Li M, Jones LS, Ibrahim TE, Kalla I, Sayinzonga-Makombe N, Isanaka S, Kanapathipillai R, Mambula C, Mouniaman I, Langendorf C, Walsh TR, Spiller OB.   +19 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Association Between Diabetes Mellitus and Cytochrome P450 Family 2 Subfamily C Member 19 (CYP2C19) Loss-of-Function Allele Carriage Among Patients Undergoing Coronary Artery Bypass Grafting: A Cross-Sectional Study. [PDF]

Cureus
Bin-Te Shawkat MS, Kabir ASMH, Ahmed I, Reza MM, Hoque Bulbul MR.   +4 more
europepmc   +1 more source