Results 71 to 80 of about 357,870 (355)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Genomic, Transcriptomic, and Phenotypic Analyses of Neisseria meningitidis Isolates from Disease Patients and Their Household Contacts

mSystems, 2017
Neisseria meningitidis (meningococcus) can cause meningococcal disease, a rapidly progressing and often fatal disease that can occur in previously healthy children.
Xiaoyun Ren, David A. Eccles, Gabrielle A. Greig, Jane Clapham, Nicole E. Wheeler, Stinus Lindgreen, Paul P. Gardner, Joanna K. MacKichan   +7 more
doaj   +1 more source

Complex driver movement mathematical model of the tractive rolling stock [PDF]

, 2018
The paper developed a complex mathematical model of the rolling stock movement that takes into account the parallel operation of two real traction asynchronous engines of the first traction railway carriage and one equivalent engine of the second ...
Dmitrienko, Valery, Glavchev, Dmitriy, Kharchenko, Artem, Mezentsev, Nikolai, Noskov, Valentin, Zakovorotniy, Alexander   +5 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Persistence and Diffusion of mecC-Positive CC130 MRSA Isolates in Dairy Farms in Meurthe-et-Moselle County (France)

Frontiers in Microbiology, 2019
Background: Methicillin resistance in Staphylococcus aureus (MRSA) is classically conferred by the acquisition of the mecA gene encoding an additional penicillin binding protein with low affinity for beta-lactams.
Jacques Bietrix, Jacques Bietrix, Camille Kolenda, Camille Kolenda, Anaïs Sapin, Marisa Haenni, Jean-Yves Madec, Michèle Bes, Michèle Bes, Michèle Bes, Céline Dupieux, Céline Dupieux, Céline Dupieux, Jason Tasse, Fréderic Laurent, Fréderic Laurent, Fréderic Laurent, Fréderic Laurent   +17 more
doaj   +1 more source

The Challenges of Using Oropharyngeal Samples To Measure Pneumococcal Carriage in Adults

mSphere, 2020
Streptococcus pneumoniae (the pneumococcus) carriage is commonly used to measure effects of pneumococcal vaccines. Based on findings from culture-based studies, the World Health Organization recommends both nasopharyngeal (NP) and oropharyngeal (OP ...
Laura K. Boelsen, Eileen M. Dunne, Katherine A. Gould, F. Tupou Ratu, Jorge E. Vidal, Fiona M. Russell, E. Kim Mulholland, Jason Hinds, Catherine Satzke   +8 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Group B Streptococcus (GBS) Carriage in Pregnant Women: Possible Emergence of Rare Serotypes and Antibiotic Resistance in Neonatal Disease

Microorganisms
Maternal vaginal and rectal colonization by Streptococcus agalactiae (group B streptococcus, GBS) is the main risk factor for the development of newborn early-onset GBS disease (GBS-EOD).
Roberta Creti, Monica Imperi, Giovanni Gherardi, Giovanna Alfarone, Ilaria Marani, Caterina Vocale, Alberto Berardi, Serena Truocchio, Francesca Miselli   +8 more
doaj   +1 more source

Role of Inflammatory Risk Factors in the Pathogenesis of Streptococcus pneumoniae

Frontiers in Immunology, 2018
Streptococcus pneumoniae (Spn) is a colonizer of the human nasopharynx (NP), causing a variety of infections in humans including otitis media, pneumonia, sepsis, and meningitis.
Ifrah Sohail, Sumit Ghosh, Santhosh Mukundan, Susan Zelewski, M. Nadeem Khan   +4 more
doaj   +1 more source