Results 111 to 120 of about 2,170,984 (299)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Self-propelled gas nanomotor-integrated microneedles for melanoma therapy: Dual-action in situ eradication and metastatic suppression

open access: yesMaterials Today Bio
Skin cancer, particularly malignant melanoma, is one of the most prevalent cancers globally, affecting millions annually. Traditional treatments like excision, chemotherapy, and immunotherapy often fail due to their invasiveness, toxicity, and poor drug ...
Chungchi Lee   +9 more
doaj   +1 more source

TYPHOID CARRIERS [PDF]

open access: yesBMJ, 1908
A, Ledingham, J C, Ledingham
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Results of a 0.03- scale aerodynamic characteristics investigation of Boeing 747 carrier (model no. AX 1319 I-1) mated with a space shuttle orbiter (model 45-0) conducted in the Boeing transonic wind tunnel (CA5), volume 1 [PDF]

open access: yes
The performance, stability, and control characteristics of various carrier aircraft configurations are presented. Aerodynamic characteristics of the carrier mated with the Orbiter, carrier alone, and Orbiter alone were investigated.
Lindahl, R. H.   +2 more
core   +1 more source

Discriminator aided phase lock acquisition for suppressed carrier signals [PDF]

open access: yes, 1982
A discriminator aided technique for acquisition of phase lock to a suppressed carrier signal utilizes a Costas loop which is initially operated open loop and control voltage for its VCXO is derived from a phase detector that compares the VCXO to a ...
Carson, L. M., Krasin, F. E.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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