Results 141 to 150 of about 2,365,470 (347)

The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading

open access: gold, 2017
Anna Baulies   +18 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Novel de novo synthesized phosphate carrier compound ABA-PEG20k-Pi20 suppresses collagenase production in Enterococcus faecalis and prevents colonic anastomotic leak in an experimental model

open access: green, 2018
Mara Wiegerinck   +9 more
openalex   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Prevalence Of Staphylococcus Aureus (SA) And Methicillin Resistant Staphylococcus Aureus (MRSA) In Personnel Of Operation Room Of Shahid Sadoughi Hospital, Yazd, Iran

open access: yesپیاورد سلامت, 2013
Background and Aim: Staphylococcus aureus(SA) may cause infection in all body organs. Many personnel and patients in hospitals may become carriers of this species.
Mohammad Bagher Khalili   +4 more
doaj  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

A review on solid dispersion: a modern formulation approach in drug delivery system

open access: yesJournal of Applied Pharmaceutical Research, 2014
Drugs those are given as solid dosage form and having low solubility often have a lack of flexibility in drug formulation and administration. The dissolution rate could be the rate-limiting process in the absorption of a drug from a solid dosage form of ...
Dheeraj Kumar Gupta   +4 more
doaj  

A possible sets of diffuse bands originating at the same carrier [PDF]

open access: bronze, 2001
T. Weselak   +3 more
openalex   +1 more source

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